Impact of early detection of respiratory viruses by multiplex PCR assay on clinical outcomes in adult patients
U Rappo, AN Schuetz, SG Jenkins… - Journal of clinical …, 2016 - Am Soc Microbiol
Rapid and definitive diagnosis of viral respiratory infections is imperative in patient triage
and management. We compared the outcomes for adult patients with positive tests for …
and management. We compared the outcomes for adult patients with positive tests for …
[HTML][HTML] Rapid multiplex PCR for respiratory viruses reduces time to result and improves clinical care: Results of a systematic review and meta-analysis
TW Clark, K Lindsley, TB Wigmosta, A Bhagat… - Journal of Infection, 2023 - Elsevier
Objectives The clinical impact of rapid sample-to-answer “syndromic” multiplex polymerase
chain reaction (PCR) testing for respiratory viruses is not clearly established. We performed …
chain reaction (PCR) testing for respiratory viruses is not clearly established. We performed …
Respiratory virus detection in immunocompromised patients with FilmArray respiratory panel compared to conventional methods
SP Hammond, LS Gagne, SR Stock… - Journal of Clinical …, 2012 - Am Soc Microbiol
Respiratory virus infections cause significant morbidity and mortality in
immunocompromised patients. Timely diagnosis is needed to provide optimal clinical care …
immunocompromised patients. Timely diagnosis is needed to provide optimal clinical care …
Comparison of two broadly multiplexed PCR systems for viral detection in clinical respiratory tract specimens from immunocompromised children
RT Hayden, Z Gu, A Rodriguez, L Tanioka… - Journal of clinical …, 2012 - Elsevier
BACKGROUND: The detection of viral respiratory tract infections has evolved greatly with
the development of PCR based commercial systems capable of simultaneously detecting a …
the development of PCR based commercial systems capable of simultaneously detecting a …
Comparison of four multiplex PCR assays for the detection of viral pathogens in respiratory specimens
TP Anderson, AM Werno, K Barratt… - Journal of Virological …, 2013 - Elsevier
Multiplex PCR has become the test of choice for the detection of multiple respiratory viruses
in clinical specimens. However, there are few direct comparisons of different PCR assays …
in clinical specimens. However, there are few direct comparisons of different PCR assays …
Clinical evaluation of multiplex real‐time PCR panels for rapid detection of respiratory viral infections
SK Sanghavi, A Bullotta, S Husain… - Journal of medical …, 2012 - Wiley Online Library
Respiratory viral infections are one of the leading causes of morbidity and mortality,
particularly in children, the elderly and immunocompromised persons. Rapid identification of …
particularly in children, the elderly and immunocompromised persons. Rapid identification of …
Clinical and economical impact of multiplex respiratory virus assays
E Vallières, C Renaud - Diagnostic microbiology and infectious disease, 2013 - Elsevier
During the last decade, a variety of molecular assays targeting respiratory viruses have
been developed and commercialized. Therefore, multiplex PCR are increasingly used in …
been developed and commercialized. Therefore, multiplex PCR are increasingly used in …
Multiplex respiratory virus testing for antimicrobial stewardship: a prospective assessment of antimicrobial use and clinical outcomes among hospitalized adults
M Semret, I Schiller, BA Jardin… - The Journal of …, 2017 - academic.oup.com
Background Respiratory tract infections are frequent causes of hospitalization and initiation
of empirical antimicrobial therapy. Testing for a broad panel of respiratory viruses has been …
of empirical antimicrobial therapy. Testing for a broad panel of respiratory viruses has been …
Detection of respiratory viruses by molecular methods
JB Mahony - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Clinical laboratories historically diagnose seven or eight respiratory virus infections using a
combination of techniques including enzyme immunoassay, direct fluorescent antibody …
combination of techniques including enzyme immunoassay, direct fluorescent antibody …
Evaluation of a multiplexed PCR assay for detection of respiratory viral pathogens in a public health laboratory setting
DJ Marshall, E Reisdorf, G Harms, E Beaty… - Journal of clinical …, 2007 - Am Soc Microbiol
There are numerous viral and bacterial causes of respiratory disease. To enable rapid and
sensitive detection of even the most prevalent causes, there is a need for more-simplified …
sensitive detection of even the most prevalent causes, there is a need for more-simplified …
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