Efficient infection of a human B cell line with cell-free Kaposi's sarcoma-associated herpesvirus

SJ Dollery, RJ Santiago-Crespo, L Kardava… - Journal of …, 2014 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is causatively linked to two B cell
lymphoproliferative disorders, multicentric Castleman's disease and primary effusion …

[HTML][HTML] KSHV manipulation of the cell cycle and apoptosis

PS Moore - Human herpesviruses: biology, therapy, and …, 2007 - ncbi.nlm.nih.gov
Disruptions of cell cycle and apoptotic regulatory control are primary hallmarks tumor cells. It
is therefore not surprising that Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8), a …

The role of Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 regulator of transcription activation (RTA) in control of gene expression

JT West, C Wood - Oncogene, 2003 - nature.com
The mechanisms that control the replication state, latency versus lytic, of human
herpesviruses have been under intense investigations. Here we summarize some of the …

Kaposi's sarcoma-associated herpesvirus latent gene vFLIP inhibits viral lytic replication through NF-κB-mediated suppression of the AP-1 pathway: a novel …

FC Ye, FC Zhou, JP Xie, T Kang, W Greene… - Journal of …, 2008 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) latency is central to the evasion of host
immune surveillances and induction of KSHV-related malignancies. The mechanism of …

Chromatinization of the KSHV genome during the KSHV life cycle

T Uppal, HC Jha, SC Verma, ES Robertson - Cancers, 2015 - mdpi.com
Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma herpesvirus family
and is the causative agent of various lymphoproliferative diseases in humans. KSHV, like …

Highly selective escape from KSHV-mediated host mRNA shutoff and its implications for viral pathogenesis

B Glaunsinger, D Ganem - The Journal of experimental medicine, 2004 - rupress.org
During Kaposi's sarcoma (KS)–associated herpesvirus (KSHV) lytic infection, many virus-
encoded signaling molecules (eg, viral G protein–coupled receptor [vGPCR]) are produced …

Today's Kaposi sarcoma is not the same as it was 40 years ago, or is it?

B Damania, DP Dittmer - Journal of medical virology, 2023 - Wiley Online Library
This review will provide an overview of the notion that Kaposi sarcoma (KS) is a disease that
manifests under diverse and divergent circumstances. We begin with a historical …

Toll-like receptor signaling controls reactivation of KSHV from latency

SM Gregory, JA West, PJ Dillon… - Proceedings of the …, 2009 - National Acad Sciences
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's
sarcoma, primary effusion lymphoma (PEL), and multicentric Castleman's disease. Like …

Kaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein kinase pathways

J Xie, H Pan, S Yoo, SJ Gao - Journal of virology, 2005 - Am Soc Microbiol
Kaposi's sarcoma is an angioproliferative disseminated tumor of endothelial cells linked to
infection with Kaposi's sarcoma-associated herpesvirus (KSHV). AP-1 transcription factors …

Kaposi's sarcoma-associated herpesvirus LANA2 is a B-cell-specific latent viral protein that inhibits p53

C Rivas, AE Thlick, C Parravicini, PS Moore… - Journal of …, 2001 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8, is associated
with three proliferative diseases ranging from viral cytokine-induced hyperplasia to …