Cytisine, a natural plant alkaloid, has been marketed in Central and Eastern Europe for over
40 years for the clinical management of smoking cessation. Despite the fact that cytisine has …

Cytisine has a molecular structure somewhat similar to that of nicotine and varenicline. The
concept for the new smoking cessation drug varenicline was based partly on cytisine. Like …

Aims To review cytisine's history of use, pre‐clinical evidence, clinical pharmacokinetics,
efficacy, adverse reactions (ARs) and safety for smoking cessation. Methods A synoptic …

Cytisine, an α4β2 nicotinic receptor partial agonist, is a plant alkaloid that is commercially
extracted for use as a smoking cessation medication. Despite its long history of use, there is …

Background Cytisine, a partial agonist that binds with high affinity to the α4β2 nicotinic
acetylcholine receptor, is a low-cost treatment that may be effective in aiding smoking …

Background Cytisine is an agonist of nicotinic receptors; in particular, it binds strongly with α
4 β 2 nicotinic receptors. Cytisine has been used to treat tobacco dependence for 40 years …

Cytisine, a natural bioactive compound that is mainly isolated from plants of the
Leguminosae family (especially the seeds of Laburnum anagyroides), has been marketed in …

Introduction Cytisinicline (known as cytisine), a nicotinic acetylcholine receptor partial
agonist, is a smoking cessation aid currently marketed in Central and Eastern Europe using …

Covering: up to the end of 2011 This review covers classical and modern structural
modifications of the alkaloid, the more recent (since 2007) syntheses of cytisine and …

Background Placebo-controlled trials indicate that cytisine, a partial agonist that binds the
nicotinic acetylcholine receptor and is used for smoking cessation, almost doubles the …