Coregulation of two embedded gene products, choline acetyltransferase and the vesicular acetylcholine transporter

S Berrard, H Varoqui, R Cervini, M Israël… - Journal of …, 1995 - Wiley Online Library
The gene encoding the vesicular acetylcholine transporter (VAChT) has recently been
localized within the first intron of the gene encoding choline acetyltransferase (ChAT) and is …

The cholinergic locus: ChAT and VAChT genes

J Mallet, L Houhou, F Pajak, Y Oda, R Cervini… - Journal of Physiology …, 1998 - Elsevier
The gene encoding the vesicular acetylcholine transporter has been localized within the first
intron of the gene encoding choline acetyltransferase and is in the same transcriptional …

Differences in the developmental expression of the vesicular acetylcholine transporter and choline acetyltransferase in the rat brain

T Hollera, B Berse, JM Cermak, MF Diebler… - Neuroscience …, 1996 - Elsevier
The neurotransmitter acetylcholine (ACh) is synthesized by the enzyme choline
acetyltransferase (ChAT) and then transported into synaptic vesicles by the vesicular …

Specific Vesicular Acetylcholine Transporter Promoters Lie within the First Intron of the Rat Choline Acetyltransferase Gene (∗)

R Cervini, L Houhou, S Béjanin, J Mallet… - Journal of Biological …, 1995 - ASBMB
The sequence encoding the vesicular acetylcholine transporter (VAChT) has recently been
localized within the first intron of the choline acetyltransferase (ChAT) gene in various …

Functional identification of a vesicular acetylcholine transporter and its expression from a “cholinergic” gene locus.

JD Erickson, H Varoqui, MK Schäfer, W Modi… - Journal of Biological …, 1994 - ASBMB
The vesicular acetylcholine transporter (VAChT) has been identified and characterized
based on the acquisition of high affinity vesamicol binding and proton-dependent, vesamicol …

Molecular cloning of a putative vesicular transporter for acetylcholine.

A Roghani, J Feldman, SA Kohan… - Proceedings of the …, 1994 - National Acad Sciences
Classical neurotransmitters such as acetylcholine (ACh) require transport into synaptic
vesicles for regulated exocytotic release. The Caenorhabditis elegans gene unc-17 encodes …

Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles

ML Gilmor, NR Nash, A Roghani… - Journal of …, 1996 - Soc Neuroscience
A cholinergic locus has recently been identified consisting of a unique mammalian genomic
arrangement containing the genes for choline acetyltransferase (ChAT) and a putative …

Identification and transgenic analysis of a murine promoter that targets cholinergic neuron expression

JM Naciff, MM Behbehani, H Misawa… - Journal of …, 1999 - Wiley Online Library
Choline acetyltransferase (ChAT) is a specific phenotypic marker of cholinergic neurons.
Previous reports showed that different upstream regions of the ChAT gene are necessary for …

The VAChT/ChAT “cholinergic gene locus”: new aspects of genetic and vesicular regulation of cholinergic function

JD Erickson, E Weihe, MKM Schäfer, E Neale… - Progress in brain …, 1996 - Elsevier
Publisher Summary This chapter focuses on the structural features of vesicular acetylcholine
transporter (VAChT) deduced from its primary sequence, which give insight into its …

More than one way to toy with ChAT and VAChT

X Castell, MF Diebler, M Tomasi, C Bigari… - Journal of Physiology …, 2002 - Elsevier
Expression of choline acetyltransferase (ChAT) and of the vesicular acetylcholine
transporter (VAChT) is required for the acquisition and the maintenance of the cholinergic …