Cellular redox homeostasis is an essential and dynamic process that ensures the balance
between reducing and oxidizing reactions within cells and regulates a plethora of biological …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are created in normal
hepatocytes and are critical for normal physiologic processes, including oxidative …

Cellular redox homeostasis is the first line of defense against diverse stimuli and is crucial
for various biological processes. Reactive oxygen species (ROS), byproducts of numerous …

Oxidative stress is a major pathogenetic event occurring in several liver disorders ranging
from metabolic to proliferative ones, and is a major cause of liver damage due to …

Living organisms use a large repertoire of anabolic and catabolic reactions to maintain their
physiological body functions, many of which include oxidation and reduction of substrates …

Redox reactions are intrinsically linked to energy metabolism. Therefore, redox processes
are indispensable for organismal physiology and life itself. The term reactive oxygen species …

Oxidative stress is a reflection of the imbalance between the production of reactive oxygen
species (ROS) and the scavenging capacity of the antioxidant system. Excessive ROS …

In the liver, the progressive accumulation of connective tissue, a complex and dynamic
process termed fibrosis, represents a very frequent event following a repeated or chronic …

Oxidative stress plays a central role in the pathogenesis of diverse chronic inflammatory
disorders including diabetic complications, cardiovascular disease, aging, and chronic …

The increased production of derivatives of molecular oxygen and nitrogen in the form of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) lead to molecular …