Oxidative stress plays a central role in the pathogenesis of diverse chronic inflammatory
disorders including diabetic complications, cardiovascular disease, aging, and chronic …

Reactive oxygen species-(ROS-) induced oxidative stress has been implicated in various
forms of diseases. Excessive ROS generation depletes the endogenous antioxidants that …

A chronic inflammatory disease is a condition characterized by persistent inflammation. A
number of human pathologies fall into this category, and a great deal of research has been …

Reactive oxygen species (ROS) were once considered to be deleterious agents,
contributing to a vast range of pathologies. But, now their protective effects are being …

Reactive oxygen species (ROS) are important cytotoxic and signalling mediators in the
pathophysiology of inflammatory liver diseases. They can be generated by resident and …

Liver disease is a highly prevalent disease that is one of the leading causes of death
worldwide. The continuous exposure of the liver to some factors such as viruses, alcohol, fat …

Liver fibrosis is the pathological consequence of chronic liver diseases, where an excessive
deposition of extracellular matrix (ECM) proteins occurs, concomitantly with the processes of …

The global concept of oxidative stress is defined as “an imbalance between oxidants and
antioxidants in favor of the oxidants, leading to a disruption of redox signaling and control …

Liver fibrosis can be considered as a dynamic and highly integrated cellular response to
chronic liver injury [1]. Whatever the etiology, the evolution of chronic liver disease (CLD) is …

GSH is the most abundant redox molecule in cells and thus the most important determinant
of cellular redox status. Thiols in proteins can undergo a wide range of reversible redox …