For many years reactive oxygen species (ROS) production in biological systems has been
considered to be detrimental. However, a pleasant face of ROS has received recently …

In the research area of redox biology, the concept of oxidative stress encompasses redox
imbalance, affecting redox signaling and leading to damage of biomolecules. Stress …

Although oxidants clearly possess the capacity to behave in a random and destructive
fashion, growing evidence suggests that in many instances the production of reactive …

Virally induced liver cancer usually evolves over long periods of time in the context of a
strongly oxidative microenvironment, characterized by chronic liver inflammation and …

Inflammation is an essential immune response characterized by pain, swelling, redness,
heat, and impaired function. A controlled acute inflammatory response is necessary to fight …

Alterations of redox homeostasis leads to a condition of resilience known as hormesis that is
due to the activation of redox-sensitive pathways stimulating cell proliferation, growth …

Macrophages are present throughout the human body, constitute important immune effector
cells, and have variable roles in a great number of pathological, but also physiological …

Oxidative stress is caused by the overproduction of Reactive Oxygen Species (ROS) and
diminished cellular antioxidant defenses. Under physiological conditions, ROS are involved …

Reactive oxygen species (ROS) are generated during mitochondrial oxidative metabolism
as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. Oxidative …

Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of
oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular …