Oxidative stress refers to elevated intracellular levels of reactive oxygen species (ROS) that
cause damage to lipids, proteins and DNA. Oxidative stress has been linked to a myriad of …

As an organ critically important for targeting and clearing viruses, bacteria, and other foreign
material, the liver operates via immune-tolerant, anti-inflammatory mechanisms …

Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants,
leading to a disruption of redox signaling and control, and/or molecular damage altering …

In humans, oxidative stress and antioxidant defenses are the sum of a complicated network
of enzymatic and non‐enzymatic processes. Depending on the stage and severity of …

Oxidative stress is importantly involved in the pathophysiology of various liver diseases. The
redox state participates on the course of the inflammatory, metabolic and proliferative liver …

Redox biology has evolved from studies of the pathology that involves oxidants to an
understanding of how oxidants participate in normal as well as aberrant signal transduction …

Tumor necrosis factor-α (TNF) is a key cytokine that has been shown to play important
physiologic (eg., inflammation) and pathophysiologic (eg., various liver pathologies) roles. In …

It has been 60 yr since the discovery of reactive oxygen species (ROS) in biology and the
beginning of the scientific community's attempt to understand the impact of the unpaired …

Reactive oxygen species (ROS), which were originally characterized in terms of their
harmful effects on cells and invading microorganisms, are increasingly implicated in various …

Oxidative stress is an increase in the reduction potential or a large decrease in the reducing
capacity of the cellular redox couples. A particularly destructive aspect of oxidative stress is …