[HTML][HTML] Cellular Red-Ox system in health and disease: The latest update

AB Jena, RR Samal, NK Bhol, AK Duttaroy - Biomedicine & …, 2023 - Elsevier
Cells are continually exposed to reactive oxygen species (ROS) generated during cellular
metabolism. Apoptosis, necrosis, and autophagy are biological processes involving a …

Redox-based regulation of signal transduction: principles, pitfalls, and promises

YMW Janssen-Heininger, BT Mossman… - Free Radical Biology …, 2008 - Elsevier
Oxidants are produced as a by-product of aerobic metabolism, and organisms ranging from
prokaryotes to mammals have evolved with an elaborate and redundant complement of …

Role of reactive oxygen species-mediated signaling in aging

VM Labunskyy, VN Gladyshev - Antioxidants & redox signaling, 2013 - liebertpub.com
Significance: Redox biology is a rapidly developing area of research due to the recent
evidence for general importance of redox control for numerous cellular functions under both …

[HTML][HTML] Targeting the redox balance in inflammatory skin conditions

FA Wagener, CE Carels, DMS Lundvig - International journal of molecular …, 2013 - mdpi.com
Reactive oxygen species (ROS) can be both beneficial and deleterious. Under normal
physiological conditions, ROS production is tightly regulated, and ROS participate in both …

Reactive oxygen species and oxidative stress

C Migdal, M Serres - Medecine Sciences: M/S, 2011 - europepmc.org
Oxidative stress is defined as an imbalance between the production of reactive oxygen
species (ROS) and the antioxidant capacity of the cell. For long, ROS have been considered …

Redox compartmentalization and cellular stress

DP Jones, YM Go - Diabetes, Obesity and Metabolism, 2010 - Wiley Online Library
Mammalian cells are highly organized to optimize function. For instance, oxidative energy‐
producing processes in mitochondria are sequestered away from plasma membrane redox …

Redox signaling at the crossroads of human health and disease

J Zuo, Z Zhang, M Luo, L Zhou, EC Nice, W Zhang… - MedComm, 2022 - Wiley Online Library
Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …

[HTML][HTML] Reactive oxygen species and redox compartmentalization

N Kaludercic, S Deshwal, F Di Lisa - Frontiers in physiology, 2014 - frontiersin.org
Reactive oxygen species (ROS) formation and signaling are of major importance and
regulate a number of processes in physiological conditions. A disruption in redox status …

ROS: basic concepts, sources, cellular signaling, and its implications in aging pathways

AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

On the history of oxidative stress: Concept and some aspects of current development

H Sies - Current Opinion in Toxicology, 2018 - Elsevier
Oxidative stress as a concept in redox biology and medicine has witnessed fulminant
development of the past 30-odd years. It is a global concept, defined as “an imbalance …