Comparison of competitive radioimmunoassays and two-site sandwich assays for the measurement and interpretation of plasma ghrelin levels
C Prudom, J Liu, J Patrie, BD Gaylinn… - The Journal of …, 2010 - academic.oup.com
Context: Ghrelin, an endogenous ligand for the GH secretagogue receptor, is an orexigenic
peptide hormone produced primarily by the stomach. Recent studies suggest significant …
peptide hormone produced primarily by the stomach. Recent studies suggest significant …
Characterization of ghrelin-like immunoreactivity in human plasma
M Patterson, KG Murphy, CW le Roux… - The Journal of …, 2005 - academic.oup.com
Ghrelin is a gastric peptide hormone that has an important role in appetite control and GH
release. Circulating ghrelin levels are inversely correlated with body mass index and …
release. Circulating ghrelin levels are inversely correlated with body mass index and …
Assessment of ghrelin.
U Espelund, TK Hansen, H Ørskov… - APMIS …, 2003 - europepmc.org
Four years ago Kojima and coworkers discovered ghrelin. Within this short lifespan ghrelin
has become one of the" hottest topics" in metabolic research, and today more than 300 …
has become one of the" hottest topics" in metabolic research, and today more than 300 …
Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men
J Liu, CE Prudom, R Nass, SS Pezzoli… - The Journal of …, 2008 - academic.oup.com
Context: Ghrelin, an acylated peptide hormone secreted from the gut, regulates appetite and
metabolism. Elucidating its pattern of secretion in the fed and fasted states is important in the …
metabolism. Elucidating its pattern of secretion in the fed and fasted states is important in the …
Optimum collection and storage conditions for ghrelin measurements: octanoyl modification of ghrelin is rapidly hydrolyzed to desacyl ghrelin in blood samples
H Hosoda, K Doi, N Nagaya, H Okumura… - Clinical …, 2004 - academic.oup.com
Ghrelin is an acylated peptide with growth-hormonereleasing activity (1). It was first isolated
from rat and human stomach during the search for an endogenous ligand to the “orphan” G …
from rat and human stomach during the search for an endogenous ligand to the “orphan” G …
Evaluation of the comparability of commercial ghrelin assays
M Groschl, M Uhr, T Kraus - Clinical chemistry, 2004 - academic.oup.com
Several assays are available to measure human ghrelin (h-GHS), but the comparability of
results among assays is unknown. As an addition to previous investigations concerning the …
results among assays is unknown. As an addition to previous investigations concerning the …
Separate measurement of plasma levels of acylated and desacyl ghrelin in healthy subjects using a new direct ELISA assay
T Akamizu, T Shinomiya, T Irako… - The Journal of …, 2005 - academic.oup.com
Two forms of ghrelin, acylated and desacyl, circulate in plasma. Although acylation is
thought to be essential for ghrelin biological activities, recent studies have suggested that …
thought to be essential for ghrelin biological activities, recent studies have suggested that …
Preanalytical influences on the measurement of ghrelin
M Gröschl, R Wagner, J Dötsch, W Rascher… - Clinical …, 2002 - academic.oup.com
Ghrelin is an acylated peptide with growth-hormonereleasing function (1, 2). It was first
isolated from rat stomach during the search for an endogenous ligand to an “orphan” G …
isolated from rat stomach during the search for an endogenous ligand to an “orphan” G …
Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans
H Ariyasu, K Takaya, T Tagami, Y Ogawa… - The Journal of …, 2001 - academic.oup.com
Ghrelin, an endogenous ligand for the GH secretagogue receptor, was isolated from rat
stomach and is involved in a novel system for regulating GH release. Although previous …
stomach and is involved in a novel system for regulating GH release. Although previous …
Plasma levels of active form of ghrelin during oral glucose tolerance test in patients with anorexia nervosa
Y Nakai, H Hosoda, K Nin, C Ooya… - European journal of …, 2003 - academic.oup.com
Objective Ghrelin is an acylated peptide, whose octanoyl modification is essential for its
biological activities. Previous studies demonstrated that fasting plasma ghrelin levels were …
biological activities. Previous studies demonstrated that fasting plasma ghrelin levels were …