Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats

C Kocak, FE Kocak, R Akcilar, OO Isiklar, H Kocak… - Life sciences, 2016 - Elsevier
Aims Acute myocardial infarction is a serious acute cardiac disorder and heart disease is still
a major public health problem in adults. We investigated the effects of embelin (EMB) and …

Cardioprotective effect of embelin on isoproterenol-induced myocardial injury in rats: possible involvement of mitochondrial dysfunction and apoptosis

BD Sahu, H Anubolu, M Koneru, JM Kumar, M Kuncha… - Life sciences, 2014 - Elsevier
Aims Preventive and/or therapeutic interventions using natural products for ischemic heart
disease have gained considerable attention worldwide. This study investigated the …

Carnosic acid promotes myocardial antioxidant response and prevents isoproterenol-induced myocardial oxidative stress and apoptosis in mice

BD Sahu, UK Putcha, M Kuncha… - Molecular and cellular …, 2014 - Springer
Carnosic acid is a well-known antioxidant. Recently, it has been identified as modulator of
nuclear factor erythroid 2-related factor 2 (Nrf2). The effect of carnosic acid in the context of …

[HTML][HTML] Cardioprotective effect of paeonol and danshensu combination on isoproterenol-induced myocardial injury in rats

H Li, YH Xie, Q Yang, SW Wang, BL Zhang, JB Wang… - PloS one, 2012 - journals.plos.org
Background Traditional Chinese medicinal herbs Cortex Moutan and Radix Salviae
Milthiorrhizaeare are prescribed together for their putative cardioprotective effects in clinical …

[HTML][HTML] Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury in rats …

M Chen, M Wang, Q Yang… - International …, 2016 - spandidos-publications.com
Oxidative stress plays an important role in the initiation and development of myocardial
injury (MI). The peroxisome proliferator-activated receptor gamma coactivator-1α (PGC …

Baicalein protects isoproterenol induced myocardial ischemic injury in male Wistar rats by mitigating oxidative stress and inflammation

M Kumar, ER Kasala, LN Bodduluru, V Dahiya… - Inflammation …, 2016 - Springer
Objective The aim of the present study was to investigate the cardioprotective effects of
baicalein, main bioactive constituent from roots of Scutellaria baicalensis and Scutellaria …

Vanillin and pentoxifylline ameliorate isoproterenol-induced myocardial injury in rats via the Akt/HIF-1α/VEGF signaling pathway

MM Elseweidy, SI Ali, MA Shaheen… - Food & Function, 2023 - pubs.rsc.org
Myocardial infarction (MI) is a major health problem associated with high morbidity and
mortality. Recently, angiogenesis has emerged as a novel therapeutic approach against …

Punicalagin attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats: Biochemical …

MM Jghef, K Boukholda, Y Chtourou, BL Fiebich… - Chemico-Biological …, 2023 - Elsevier
Myocardial infarction (MI) is a life-threatening ischemic disease and is one of the leading
causes of morbidity and mortality worldwide. Punicalagin (PU), the major ellagitannin found …

[HTML][HTML] Protective effects of p-nitro caffeic acid phenethyl ester on acute myocardial ischemia-reperfusion injury in rats

Q Du, C Hao, J Gou, X Li, K Zou… - Experimental and …, 2016 - spandidos-publications.com
Myocardial ischemia-reperfusion (IR) causes widespread cardiomyocyte dysfunction,
including apoptosis and necrosis. The present study aimed to investigate the possible …

Cardioprotective effect of mangiferin on isoproterenol induced myocardial infarction in rats

S Prabhu, M Jainu, KE Sabitha, CS Devi - 2006 - nopr.niscpr.res.in
Isoproterenol (ISPH) induced myocardial infarction was confirmed by disturbances in serum
and heart tissue marker enzymes such as lactate dehydrogenase (LDH), creatine phospho …