Immune activation has been recently found to play a large part in the development of
schizophrenia, but the underlying mechanism remains largely unknown. Here, we report the …

Parkinson's disease and schizophrenia are disease end points of dopaminergic deficit and
hyperactivity, respectively in the mid brain. Accordingly, current pharmacological …

Proteomics provides the opportunity to visualise, quantify and hypothesise differences in
protein expression, functions and interactions with the possibility of elucidating the …

Schizophrenia (SCZ) is a highly heterogeneous disorder with diverse clinical manifestations
and macro-and microscale biological variations, usually observed at dissociable levels …

Background High-throughput expression analyses of postmortem brain tissue have been
widely used to study bipolar disorder and schizophrenia. However, despite the extensive …

We have previously demonstrated functional and molecular changes in hippocampal
subfields in individuals with schizophrenia (SZ) psychosis associated with hippocampal …

ABSTRACT Bipolar Disorder (BPD) and Schizophrenia (SCZ) are complex psychiatric
disorders with shared symptomatology and genetic risk factors. Understanding the …

Background Striatal medium spiny neurons (MSNs) are preferentially lost in Huntington's
disease. Genomic studies also implicate a direct role for MSNs in schizophrenia, a …

Psychiatric disorders like schizophrenia, bipolar disorder, and major depressive disorder
exhibit significant genetic and clinical overlap. However, their molecular architecture …

Background Impaired glutamatergic signaling is believed to underlie auditory cortex
pyramidal neuron dendritic spine loss and auditory symptoms in schizophrenia. Many …