[HTML][HTML] Clinically translatable gold nanozymes with broad spectrum antioxidant and anti-inflammatory activity for alleviating acute kidney injury
DY Zhang, T Tu, MR Younis, KS Zhu, H Liu, S Lei… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Acute kidney injury (AKI) is associated with aberrant generation of oxidative
species and inflammation, leading to high mortality of in-hospitalized patients. Although N …
species and inflammation, leading to high mortality of in-hospitalized patients. Although N …
Novel gold-platinum nanoparticles serve as broad-spectrum antioxidants for attenuating ischemia reperfusion injury of the kidney
S Feng, Y Qu, B Chu, X Chen, Z Yang, P Li, P Wang… - Kidney International, 2022 - Elsevier
Kidney ischemia reperfusion injury (IRI) is a common and inevitable pathological condition
in routine urological practices, especially during transplantation. Severe kidney IRI may …
in routine urological practices, especially during transplantation. Severe kidney IRI may …
Engineered nanodrug targeting oxidative stress for treatment of acute kidney injury
Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid decline in renal
function, and is associated with a high risk of death. Many pathological changes happen in …
function, and is associated with a high risk of death. Many pathological changes happen in …
Natural metal polyphenol nanozyme: free radical scavenging and antioxidation for the treatment of acute kidney injury
H Yuan, F Wang, Z Wang, D Gu, W Huang… - ACS Materials …, 2023 - ACS Publications
Acute kidney injury (AKI) is a severe renal dysfunction syndrome associated with high
morbidity and mortality. Excessive production of reactive oxygen/nitrogen species (RONS) is …
morbidity and mortality. Excessive production of reactive oxygen/nitrogen species (RONS) is …
Tailoring Oxidation Responsiveness of Gold Nanoclusters via Ligand Engineering for Imaging Acute Kidney Injury
S Li, N Yang, Q Ma, S Li, S Tong, J Luo… - Analytical …, 2023 - ACS Publications
Gold nanoclusters (AuNCs) have shown great promise for in vivo imaging because of their
definable structure, tunable photoluminescence (PL), and desired renal clearance …
definable structure, tunable photoluminescence (PL), and desired renal clearance …
Engineering antioxidative cascade metal-phenolic nanozymes for alleviating oxidative stress during extracorporeal blood purification
Oxidative stress is a compelling risk factor in chronic kidney diseases and is further
aggravated for individuals during extracorporeal blood purification, ultimately leading to …
aggravated for individuals during extracorporeal blood purification, ultimately leading to …
Inflammation-sensing catalase-mimicking nanozymes alleviate acute kidney injury via reversing local oxidative stress
Background The reactive oxygen species (ROS) and inflammation, a critical contributor to
tissue damage, is well-known to be associated with various disease. The kidney is …
tissue damage, is well-known to be associated with various disease. The kidney is …
Biodegradable Self‐Assembled Ultrasmall Nanodots as Reactive Oxygen/Nitrogen Species Scavengers for Theranostic Application in Acute Kidney Injury
Acute kidney injury (AKI) is frequently triggered by abundant reactive oxygen/nitrogen
species (RONS) and leads to high morbidity and mortality in clinic. Unfortunately, the current …
species (RONS) and leads to high morbidity and mortality in clinic. Unfortunately, the current …
pH‐Activatable Pre‐Nanozyme Mediated H2S Delivery for Endo‐Exogenous Regulation of Oxidative Stress in Acute Kidney Injury
W Jiang, X Hou, Y Qi, Z Wang, Y Liu, XJ Gao… - Advanced …, 2024 - Wiley Online Library
Oxidative stress induced by excess reactive oxygen species (ROS) is a primary pathogenic
cause of acute kidney injury (AKI). Development of an effective antioxidation system to …
cause of acute kidney injury (AKI). Development of an effective antioxidation system to …
Mackinawite nanozymes as reactive oxygen species scavengers for acute kidney injury alleviation
Z Xu, Y Zhu, M Xie, K Liu, L Cai, H Wang, D Li… - Journal of …, 2023 - Springer
Background Iron sulfide nanomaterials have been successfully employed as therapeutic
agents for bacterial infection therapy and catalytic-ferroptosis synergistic tumor therapy due …
agents for bacterial infection therapy and catalytic-ferroptosis synergistic tumor therapy due …