Genetics is the branch of biology concerned with study of individual genes and how they
work whereas genomics is involved with the analysis of all genes and their interactions. Both …

Cystic fibrosis (CF) is a complicated disease involving many organ systems. Identification of
the cystic fibrosis transmembrane regulator (CFTR) genetic code has not only enhanced our …

The positional cloning of the gene responsible for cystic fibrosis (CF) was the important first
step in understanding the basic defect and pathophysiology of the disease. This study aims …

Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the cystic
fibrosis transmembrane conductance regulator (CFTR) gene. The disease is characterized …

The present report describes several aspects of the relationship of mutations in the cystic
fibrosis (CF) transmembrane conductance regulator (CFTR) gene to phenotype expression …

The availability of the human genome sequence and tools for interrogating individual
genomes provide an unprecedented opportunity to apply genetics to medicine. Mendelian …

There are numerous methodologies available for the analysis of genomic CFTR DNA. We
present here the basic tools to allow a thorough investigation of the CFTR gene, beginning …

Cystic fibrosis (CF) is a monogenic disease caused by mutations of the cystic fibrosis
transmembrane conductance regulator (CFTR) gene. The genotype-phenotype relationship …

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator
(CFTR) gene, which encodes a protein expressed in the apical membrane of exocrine …

The causative gene in cystic fibrosis (CF) was identified in 1989, 3 years before the
publication of the first issue of Human Molecular Genetics. The cystic fibrosis …