[HTML][HTML] Current concepts in the pathogenesis of osteoarthritis

S Krasnokutsky, M Attur, G Palmer, J Samuels… - Osteoarthritis and …, 2008 - Elsevier
Osteoarthritis (OA) is a degenerative joint disease that progressively causes loss of joint
function and is the leading source of physical disability and impaired quality of life in …

Bone loss: Therapeutic approaches for preventing bone loss in inflammatory arthritis

Q Rehman, NE Lane - Arthritis Research & Therapy, 2001 - Springer
Inflammatory arthritides are commonly characterized by localized and generalized bone
loss. Localized bone loss in the form of joint erosions and periarticular osteopenia is a …

Nutraceutical activity in osteoarthritis biology: a focus on the nutrigenomic role

S D'Adamo, S Cetrullo, V Panichi, E Mariani… - Cells, 2020 - mdpi.com
Osteoarthritis (OA) is a disease associated to age or conditions that precipitate aging of
articular cartilage, a post-mitotic tissue that remains functional until the failure of major …

Osteoarthritis and nitric oxide

SB Abramson - Osteoarthritis and cartilage, 2008 - Elsevier
Osteoarthritis (OA) is caused by both biochemical and mechanical factors. While the
mechanisms that underlie the disease are not completely understood, investigators have …

Inflammation in bone physiology and pathology

IE Adamopoulos - Current opinion in rheumatology, 2018 - journals.lww.com
Inflammation in bone physiology and pathology : Current Opinion in Rheumatology
Inflammation in bone physiology and pathology : Current Opinion in Rheumatology Log in …

Inflammation-induced bone loss: can it be prevented?

E Romas, MT Gillespie - Rheumatic Disease Clinics, 2006 - rheumatic.theclinics.com
A defining feature of rheumatoid arthritis (RA) is its propensity to destroy cartilage and bone
[1]. The presence of bone erosions indicates irreversible joint damage and it is associated …

Aberrant reactive oxygen and nitrogen species generation in rheumatoid arthritis (RA): causes and consequences for immune function, cell survival, and therapeutic …

DC Phillips, HKI Dias, GD Kitas… - Antioxidants & redox …, 2010 - liebertpub.com
The infiltration and persistence of hematopoietic immune cells within the rheumatoid arthritis
(RA) joint results in elevated levels of pro-inflammatory cytokines, increased reactive oxygen …

Nitric oxide in inflammation and pain associated with osteoarthritis

SB Abramson - Arthritis research & therapy, 2008 - Springer
Osteoarthritis (OA) is a degenerative disease involving chondrocytes, cartilage and other
joint tissues, and has a number of underlying causes, including both biochemical and …

Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations

J Sokolove, CM Lepus - Therapeutic advances in …, 2013 - journals.sagepub.com
Osteoarthritis (OA) has traditionally been classified as a noninflammatory arthritis; however,
the dichotomy between inflammatory and degenerative arthritis is becoming less clear with …

Effects of rheumatoid arthritis on bone

G Haugeberg, RE Ørstavik… - Current opinion in …, 2003 - journals.lww.com
The effects of rheumatoid arthritis on bone include structural joint damage (erosions) and
osteoporosis. The latter may lead to increased risk for fractures, which are associated with …