Over the past century researchers have identified normal genetic variation and studied that
variation in diverse human populations to determine the amounts and distributions of that …

The past two decades have witnessed an explosion of human genetic data. Innumerable
DNA sequences and genotypes have been generated, and they have led to significant …

The complete human genome nucleotide sequence and technologies for assessing
sequence variation on a genome–scale will prompt comprehensive studies of comparative …

Nucleotides of the Human Genome? Page 1 Am. J. Hum. Genet. 46:649-651, 1990 Opinion:
How Can One Study Individual Variation for 3 Billion Nucleotides of the Human Genome? L …

Abstract The last 50,000–150,000 years of human history have been characterized by rapid
demographic expansions and the colonization of novel environments outside of sub …

Human DNA sequence variation data are useful for studying the origin, evolution, and
demographic history of modern humans and the mechanisms of maintenance of genetic …

The international Human Genome Project (HGP) is an effort to map and then sequence the
human genome, that is, to determine the DNA sequence of all 3 billion nucleotide base pairs …

Despite our relatively large population size, humans are genetically less variable than other
primates. Many allele frequencies and statistical descriptors of genome diversity form broad …

Abstract The Human Genome Project, in accomplishing its goal of sequencing one human
genome, heralded a new era of research, a component of which is the systematic study of …

Regions of the genome showing high evolutionary stability are often conserved as a result of
functional constraints. Conversely, more variable regions are likely to represent DNA with no …