Relevance of distinct monocyte subsets to clinical course of ischemic stroke patients

M Kaito, SI Araya, Y Gondo, M Fujita, N Minato… - PLoS one, 2013 - journals.plos.org
Background and Purpose The most common strategy for treating patients with acute
ischemic stroke is thrombolytic therapy, though only a few patients receive benefits because …

Monocyte subtypes predict clinical course and prognosis in human stroke

X Urra, N Villamor, S Amaro… - Journal of Cerebral …, 2009 - journals.sagepub.com
The number of circulating monocytes increases after stroke. In this study, we assessed the
time course and phenotype of monocyte subsets and their relationship with the clinical …

Monocytes are major players in the prognosis and risk of infection after acute stroke

X Urra, A Cervera, V Obach, N Climent, AM Planas… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Monocytes participate in adaptive and innate immune
responses. Monocyte numbers increase in patients with stroke associated infection (SAI) or …

Monocyte‐related cytokines/chemokines in cerebral ischemic stroke

M Bai, R Sun, B Cao, J Feng… - CNS Neuroscience & …, 2023 - Wiley Online Library
Aims Ischemic stroke is one of the leading causes of death worldwide and the most common
cause of disability in Western countries. Multiple mechanisms contribute to the development …

The role of monocytes in ischemic stroke pathobiology: new avenues to explore

A ElAli, N Jean LeBlanc - Frontiers in aging neuroscience, 2016 - frontiersin.org
Ischemic stroke accounts for the majority of stroke cases and constitutes a major cause of
death and disability in the industrialized world. Inflammation has been reported to constitute …

Thrombo-inflammation in acute ischaemic stroke—implications for treatment

G Stoll, B Nieswandt - Nature Reviews Neurology, 2019 - nature.com
Ischaemic stroke elicits a strong neuroinflammatory response, but the functional relevance
and therapeutic potential of neuroinflammation has only recently become apparent. In acute …

[HTML][HTML] Peripheral immune cell counts and advanced imaging as biomarkers of stroke outcome

H Pagram, A Bivard, LF Lincz, C Levi - Cerebrovascular Diseases Extra, 2017 - karger.com
Introduction: Circulating neutrophil and lymphocyte levels may be modifiable outcome
predictors of ischemic stroke. We sought to compare these immune cell parameters with …

[HTML][HTML] The local and peripheral immune responses to stroke: implications for therapeutic development

KA Zera, MS Buckwalter - Neurotherapeutics, 2020 - Elsevier
The immune response to stroke is an exciting target for future stroke therapies. Stroke is a
leading cause of morbidity and mortality worldwide, and clot removal (mechanical or …

Temporal dynamics of peripheral neutrophil and lymphocytes following acute ischemic stroke

AB Petrone, RD Eisenman, KN Steele… - Neurological …, 2019 - Springer
Background The immune response to acute ischemic stroke (AIS) is implicated in diagnosis,
prognosis, and intervention; however, the temporal dynamics of leukocytes following AIS are …

[HTML][HTML] The prognostic value of serum cytokines in patients with acute ischemic stroke

X Li, S Lin, X Chen, W Huang, Q Li, H Zhang… - Aging and …, 2019 - ncbi.nlm.nih.gov
The inflammatory response is an unavoidable process and contributes to the destruction of
cerebral tissue during the acute ischemic stroke (AIS) phase and has not been addressed …