Gallstone disease (GSD) is the result of the interaction between genetic and environmental
factors and it is a major disease cause of surgery with high costs to health systems …

Cholesterol gallstone formation is a multifactorial process involving a multitude of metabolic
pathways. The primary pathogenic factor is hypersecretion of free cholesterol into bile. For …

Cholesterol gallstone disease, one of the commonest digestive diseases in western
countries, is induced by an imbalance in cholesterol metabolism, which involves intestinal …

Cholesterol cholelithiasis is one of the most common gastroenterological diseases in
Western countries. It is a polygenic disease resulting from disturbed biliary cholesterol …

Gallstone disease (GSD) is one of the most common biliary tract disorders worldwide. The
prevalence, however, varies from 5.9–21.9% in Western society to 3.1–10.7% in Asia. Most …

Cholelithiasis is one of the most prevalent gastroenterological diseases, imposing a huge
economic burden on health-care systems. Gallbladder stones form when the concentration …

Gallstone disease is one of the most prevalent gastrointestinal diseases with a substantial
burden to health care systems that is supposed to increase in ageing populations at risk …

Gallstone disease is a complex disorder where both environmental and genetic factors
contribute towards susceptibility to the disease. Epidemiological and family studies suggest …

Cholesterol cholelithiasis is a common digestive disease, the etiology and the pathogenesis
of cholesterol gallstones (GS) have not been elucidated. Family and epidemiological studies …

Cholelithiasis is one of the most prevalent and most expensive gastroenterologic diseases. It
belongs to the group of complex metabolic disorders that affect humans, and its critical …