Cardiovascular responses to intravenous administration of human hemokinin-1 and its truncated form hemokinin-1 (4-11) in anesthetized rats

ZQ Kong, CY Fu, Q Chen, R Wang - European journal of pharmacology, 2008 - Elsevier
Human hemokinin-1 and its carboxy-terminal fragment human hemokinin-1 (4-11) have
been recently identified as the members of the tachykinin family. The peripheral …

Cardiovascular responses to rat/mouse hemokinin-1, a mammalian tachykinin peptide: systemic study in anesthetized rats

CY Fu, ZQ Kong, Y Long, Q Chen, R Wang - European journal of …, 2007 - Elsevier
Rat/mouse hemokinin-1 is a mammalian tachykinin peptide whose biological functions have
not been well characterized. In the present study, an attempt has been made to investigate …

Effects of rat/mouse hemokinin-1, human hemokinin-1 and human hemokinin-1 (4-11), mammalian tachykinin peptides, on rate and perfusion pressure in the isolated …

ZQ Kong, WL Yang, Y Tao, XM Shi, CY Fu, RF Zhao… - Neuropeptides, 2010 - Elsevier
Rat/mouse hemokinin-1 (r/m HK-1), human hemokinin-1 (h HK-1) and human hemokinin-1
(4-11)(h HK-1 (4-11)) are members of the tachykinin family. In the present study, the …

Mechanisms of relaxing response induced by rat/mouse hemokinin-1 in porcine coronary arteries: roles of potassium ion and nitric oxide

Y Long, CY Fu, XZ Tian, J Chen, M Han… - European journal of …, 2007 - Elsevier
Rat and mouse hemokinin-1 (r/m hemokinin-1) is a recently described member of the
tachykinin family whose cardiovascular functions are not fully understood. In this study, we …

Pharmacological profile of hemokinin 1: a novel member of the tachykinin family

V Camarda, A Rizzi, G Calo, R Guerrini, S Salvadori… - Life sciences, 2002 - Elsevier
Recently, the cloning of a novel preprotachykinin gene (PPT-C) has been reported. This
gene codes for a novel peptide named hemokinin 1 (HK-1). In contrast with the known …

The N-terminal domain of human hemokinin-1 influences functional selectivity property for tachykinin receptor neurokinin-1

L Mou, Y Xing, Z Kong, Y Zhou, Z Chen… - Biochemical …, 2011 - Elsevier
Human hemokinin-1 (hHK-1) is a substance P-like tachykinin peptide preferentially
expressed in non-neuronal tissues. It is involved in multiple physiological functions such as …

[HTML][HTML] Pharmacological profile of the novel mammalian tachykinin, hemokinin 1

F Bellucci, F Carini, C Catalani, P Cucchi… - British journal of …, 2002 - ncbi.nlm.nih.gov
Pharmacological profile of the novel mammalian tachykinin, hemokinin 1 - PMC Back to Top
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Characterization of the endokinins: human tachykinins with cardiovascular activity

NM Page, NJ Bell, SM Gardiner… - Proceedings of the …, 2003 - National Acad Sciences
We report four human tachykinins, endokinins A, B, C, and D (EKA–D), encoded from a
single tachykinin precursor 4 gene that generates four mRNAs (α, β, γ, and δ). Tachykinin 4 …

Functional characterisation of hemokinin-1 in mouse uterus

E Patak, JN Pennefather, M Gozali, L Candenas… - European journal of …, 2008 - Elsevier
The preprotachykinin gene Tac4 expressed in murine uterus and placenta is thought to
encode a peptide RSRTRQFYGLM-NH2, mouse hemokinin 1. We have examined the …

Tachykinins and the cardiovascular system

DA Walsh, DF McWilliams - Current drug targets, 2006 - ingentaconnect.com
The tachykinin family of vasoactive peptides comprises the neuropeptides substance P,
neurokinin A and neurokinin B, and the newly discovered endokinins and hemokinins. Their …