Captopril (10 mg/kg, ip) increased the arterial bradykinin (BK) level (Art-BK) of non-treated
Sprague-Dawley rats (SD), determined by an ELISA, from 10.8±3.2 pg/ml to 32.9±5.4 pg/ml …

In this study, we evaluated the bradykinin potentiating activity and ACE inhibitory activity of
several Ang-(1–7)-related peptides: Ang-(2–7), Ang-(3–7), Ang-(4–7), Ang-(1–6), Ang-(1–5) …

A family of peptides that shares a common C-terminal sequence (Phe-X-Gly-Leu-MetNH 2)
exists in mammalian and non-mammalian species. In mammals, three of these peptides …

Bradykinin (BK), a product of plasma kallikrein-kinin system, is one of most potent,
endogenous vasodilator substances. Therefore, physiological and pathophysiological roles …

Kinins are vasoactive peptides that play important roles in cardiovascular homeostasis, pain
and inflammation. After release from their precursor kininogens, kinins or their C-terminal …

Substance P (SP), neurokinin A (NU) and neurokinin H (NKH) are members of a family of
neuropeptides referred to as the tachykinins, on account of their ability to induce rapid …

We studied the role of brain kinins in the regulation of cardiovascular function.
Intracerebroventricular injection of 380 pmol bradykinin increased mean blood pressure by …

Type 2 bradykinin (B2)-receptor antagonists have been used to define the role of
endogenous kinin peptides. However, interpretation of the effects of B2-receptor antagonists …

Hemodynamic effects of the kallikrein–kinin system can be investigated by experimental
administration of specific kinin antagonists and by measurement of kinin levels in the …

Bradykinin (BK), a nonapeptide derived from kininogen, is involved in a variety of biological
processes including inflammation, regulation of blood pressure and fluid and electrolyte …