Higher frequencies of BCRP+ cardiac resident cells in ischaemic human myocardium

MY Emmert, LS Emmert, A Martens, I Ismail… - European Heart …, 2013 - academic.oup.com
Aims Several cardiac resident progenitor cell types have been reported for the adult
mammalian heart. Here we characterize their frequencies and distribution pattern in non …

Isolation and characterization of cardiogenic, stem-like cardiac precursors from heart samples of patients with congenital heart disease

Z Ghazizadeh, S Vahdat, F Fattahi, H Fonoudi… - Life sciences, 2015 - Elsevier
Aims Regenerative therapies based on resident human cardiac progenitor cells (hCPCs)
are a promising alternative to medical treatments for patients with myocardial infarction …

Cardiac resident progenitor cells: evidence and functional significance

K Guan, G Hasenfuss - European heart journal, 2013 - academic.oup.com
It has been estimated that a serious myocardial infarction (MI) results in the loss of 1 billion
functional cardiomyocytes, which are replaced with a fibrous scar, frequently leading to heart …

Patient characteristics and cell source determine the number of isolated human cardiac progenitor cells

A Itzhaki-Alfia, J Leor, E Raanani, L Sternik… - Circulation, 2009 - Am Heart Assoc
Background—The identification and isolation of human cardiac progenitor cells (hCPCs)
offer new approaches for myocardial regeneration and repair. Still, the optimal source of …

Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification

C Vicinanza, I Aquila, M Scalise, F Cristiano… - Cell Death & …, 2017 - nature.com
Multipotent adult resident cardiac stem cells (CSCs) were first identified by the expression of
c-kit, the stem cell factor receptor. However, in the adult myocardium c-kit alone cannot …

Bone marrow is a reservoir for cardiac resident stem cells

N Liu, X Qi, Z Han, L Liang, D Kong, Z Han, S Zhao… - Scientific Reports, 2016 - nature.com
Resident cardiac stem cells (CSCs) represent a responsive stem cell reservoir within the
adult myocardium and have a significant function in myocardial homeostasis and injury …

Resident cardiac stem cells

KV Dergilev, KA Rubina, EV Parfenova - Kardiologiia, 2011 - europepmc.org
The search for sources of stem/progenitor cells the use of which has a potential to affect
course of ischemic heart disease and chronic heart failure is conducted nowadays in many …

Distribution of cardiac stem cells in the human heart

M Arsalan, F Woitek, V Adams, A Linke… - International …, 2012 - Wiley Online Library
Introduction. The existence of human cardiac stem cells (hCSC) and their regenerative
capacity are not fully defined. The aim of this study was to identify and analyse the …

Characterization and growth of human cardiac stem cells

C Bearzi, S Cascapera, A Nascimbene, C Casarsa… - Circulation, 2005 - iris.unito.it
The human heart contains a subpopulation of replicating myocytes that is enhanced in
pathologic states characterized by acute and chronic cardiac failure. On the assumption that …

Increase of ABCG2/BCRP+ side population stem cells in myocardium after ventricular unloading

J Wohlschlaeger, B Levkau, A Takeda… - The Journal of heart and …, 2012 - Elsevier
BACKGROUND: A significant decrease in mean cardiomyocyte DNA content and increased
numbers of diploid cardiomyocytes after unloading has been demonstrated, suggesting a …