[HTML][HTML] Targeting the endocannabinoid system to treat anxiety-related disorders

N Korem, TM Zer-Aviv, E Ganon-Elazar… - Journal of basic and …, 2016 - degruyter.com
The endocannabinoid system plays an important role in the control of emotions, and its
dysregulation has been implicated in several psychiatric disorders. The most common self …

Endocannabinoid system and exogenous cannabinoids in depression and anxiety: a review

A Hasbi, BK Madras, SR George - Brain Sciences, 2023 - mdpi.com
Background: There is a growing liberalization of cannabis-based preparations for medical
and recreational use. In multiple instances, anxiety and depression are cited as either a …

Endocannabinoids, cannabinoids and the regulation of anxiety

GN Petrie, AS Nastase, RJ Aukema, MN Hill - Neuropharmacology, 2021 - Elsevier
Cannabis has been used for hundreds of years, with its ability to dampen feelings of anxiety
often reported as a primary reason for use. Only recently has the specific role cannabinoids …

Cannabinoids and the endocannabinoid system in anxiety, depression, and dysregulation of emotion in humans

VL Chadwick, C Rohleder, D Koethe… - Current Opinion in …, 2020 - journals.lww.com
Cannabinoids and the endocannabinoid system in anxiety, depr... : Current Opinion in
Psychiatry Cannabinoids and the endocannabinoid system in anxiety, depression, and …

The endocannabinoid system and the treatment of mood and anxiety disorders

MN Hill, BB Gorzalka - … (Formerly Current Drug Targets-CNS & …, 2009 - ingentaconnect.com
The central endocannabinoid system is a neuroactive lipid signalling system in the brain
which acts to control neurotransmitter release. The expression patterns of this system …

Cannabinoids and emotionality: a neuroanatomical perspective

RJ McLaughlin, G Gobbi - Neuroscience, 2012 - Elsevier
The endocannabinoid system has recently emerged as a promising therapeutic target for the
treatment of stress-related emotional disorders. A growing literature base has collectively …

The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses

MN Hill, M Haney, CJ Hillard, DS Karhson… - Psychological …, 2023 - cambridge.org
Cannabis is well established to impact affective states, emotion and perceptual processing,
primarily through its interactions with the endocannabinoid system. While cannabis use is …

Toward a translational approach to targeting the endocannabinoid system in posttraumatic stress disorder: a critical review of preclinical research

S Papini, GM Sullivan, DA Hien, E Shvil, Y Neria - Biological Psychology, 2015 - Elsevier
Despite the lack of clinical research, marijuana and synthetic cannabinoids have been
approved to treat posttraumatic stress disorder (PTSD) in several states in the United States …

Cannabinoid regulation of fear and anxiety: an update

EP Papagianni, CW Stevenson - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review Anxiety-and trauma-related disorders are prevalent and
debilitating mental illnesses associated with a significant socioeconomic burden. Current …

Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid …

S Patel, CJ Hillard - Journal of Pharmacology and Experimental …, 2006 - ASPET
Extracts of Cannabis sativa have been used for their calming and sedative effects for
centuries. Recent developments in drug discovery have suggested that modulation of …