Background Antibodies raised against human seasonal coronaviruses (sCoVs), which are
responsible for the common cold, are known to cross-react with SARS-CoV-2 antigens. This …

The humoral immune response plays a key role in suppressing the pathogenesis of SARS-
CoV-2. The molecular determinants underlying the neutralization of the virus remain …

SARS-CoV-2 variants of concern (VOCs) have emerged worldwide, with implications on the
spread of the pandemic. Characterizing the cross-reactivity of antibodies against these …

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread
around the world, there is an urgent need for new assay formats to characterize the humoral …

Abstract Background The SARS-CoV-2 pandemic currently prevails worldwide. To
understand the immunological signature of SARS-CoV-2 infections and aid the search and …

Antibody responses develop following SARS-CoV-2 infection, but little is known about their
epitope specificities, clonality, binding affinities, epitopes, and neutralizing activity. We …

SARS-CoV-2-specific antibodies, particularly those preventing viral spike receptor binding
domain (RBD) interaction with host angiotensin-converting enzyme 2 (ACE2) receptor, can …

ABSTRACT S evere a cute r espiratory s yndrome co rona v irus 2 (SARS-CoV-2) has
caused a global pandemic of COVID-19, resulting in cases of mild to severe respiratory …

The humoral response to the SARS-CoV-2 S protein determines the development of
protective immunity against this infection. The standard neutralizing antibodies detection …

Both the SARS-CoV-2 pandemic and emergence of variants of concern have highlighted the
need for functional antibody assays to monitor the humoral response over time. Antibodies …