[HTML][HTML] Expression signatures that correlated with Gleason score and relapse in prostate cancer
M Bibikova, E Chudin, A Arsanjani, L Zhou, EW Garcia… - Genomics, 2007 - Elsevier
Predicting prognosis in prostate carcinoma remains a challenge when using clinical and
pathologic criteria only. We used an array-based DASL® assay to identify molecular …
pathologic criteria only. We used an array-based DASL® assay to identify molecular …
Molecular classification of prostate cancer using curated expression signatures
High Gleason score is currently the best prognostic indicator for poor prognosis in prostate
cancer. However, a significant number of patients with low Gleason scores develop …
cancer. However, a significant number of patients with low Gleason scores develop …
[HTML][HTML] Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy
Purpose Clinicopathologic features and biochemical recurrence are sensitive, but not
specific, predictors of metastatic disease and lethal prostate cancer. We hypothesize that a …
specific, predictors of metastatic disease and lethal prostate cancer. We hypothesize that a …
[HTML][HTML] Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer
TJ McDonnell, NS Chari, JH Cho-Vega… - BMC medical …, 2008 - Springer
Background: The early detection of prostate cancer has resulted in an increase in the
number of patients with localized prostate cancer and has paralleled the reported reduction …
number of patients with localized prostate cancer and has paralleled the reported reduction …
[HTML][HTML] Gene expression signature of Gleason score is associated with prostate cancer outcomes in a radical prostatectomy cohort
MA Jhun, MS Geybels, JL Wright, S Kolb, C April… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is a leading cause of cancer-related mortality worldwide. Gleason
score (GS) is one of the best predictors of PCa aggressiveness, but additional tumor …
score (GS) is one of the best predictors of PCa aggressiveness, but additional tumor …
[HTML][HTML] Gene expression profiling predicts clinical outcome of prostate cancer
GV Glinsky, AB Glinskii, AJ Stephenson… - The Journal of …, 2004 - Am Soc Clin Investig
One of the major problems in management of prostate cancer is the lack of reliable genetic
markers predicting the clinical course of the disease. We analyzed expression profiles of …
markers predicting the clinical course of the disease. We analyzed expression profiles of …
Development and validation of a 32-gene prognostic index for prostate cancer progression
CL Wu, BE Schroeder, XJ Ma… - Proceedings of the …, 2013 - National Acad Sciences
The accurate determination of the risk of cancer recurrence is an important unmet need in
the management of prostate cancer. Patients and physicians must weigh the benefits of …
the management of prostate cancer. Patients and physicians must weigh the benefits of …
Integration of gene expression profiling and clinical variables to predict prostate carcinoma recurrence after radical prostatectomy
AJ Stephenson, A Smith, MW Kattan… - … Journal of the …, 2005 - Wiley Online Library
BACKGROUND Gene expression profiling of prostate carcinoma offers an alternative means
to distinguish aggressive tumor biology and may improve the accuracy of outcome …
to distinguish aggressive tumor biology and may improve the accuracy of outcome …
Construction of a set of novel and robust gene expression signatures predicting prostate cancer recurrence
We report here numerous novel genes and multiple new signatures which robustly predict
prostate cancer (PC) recurrence. We extracted 696 differentially expressed genes relative to …
prostate cancer (PC) recurrence. We extracted 696 differentially expressed genes relative to …
[HTML][HTML] Five-gene signature associating with Gleason score serve as novel biomarkers for identifying early recurring events and contributing to early diagnosis for …
L Zhang, Y Li, X Wang, Y Ping, D Wang, Y Cao… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Compared to non-recurrent type, recurrent prostate adenocarcinoma (PCa) is
highly fatal, and significantly shortens the survival time of affected patients. Early and …
highly fatal, and significantly shortens the survival time of affected patients. Early and …