Multiple sclerosis (MS) is a chronic debilitating disease of the central nervous system
primarily mediated by T lymphocytes with specificity to neuronal antigens in genetically …

Introduction Multiple sclerosis (MS) is a complex genetic disease characterized by chronic
inflammation of the central nervous system (CNS). The pathology of MS is largely attributed …

The role of CD8+ T cells in multiple sclerosis (MS) and its animal models has been
enigmatic. Most studies of MS have focused on the role of CD4+ Th1 T cells and many …

Multiple sclerosis (MS) is an inflammatory disease in which the myelin sheaths around the
axons of the brain and spinal cord are damaged, leading to demyelination and scarring as …

The dysregulation of inflammatory responses and of immune self-tolerance is considered to
be a key element in the autoreactive immune response in multiple sclerosis (MS) …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) in which the immune system damages the protective insulation surrounding the nerve …

Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by the
progressive loss of axonal myelin in several areas of the central nervous system (CNS) that …

Animal models of autoimmune diseases such as experimental autoimmune
encephalomyelitis (EAE) are inflammatory demyelinating diseases which comprise a …

Multiple sclerosis (MS) is considered to be a T cell-mediated autoimmune disease that
results in the presence of inflammatory lesions/plaques associated with mononuclear cell …

Regulatory T (Treg) cells are a special subpopulation of immunosuppressive T cells that are
essential for sustaining immune homeostasis. They maintain self‐tolerance, inhibit …