Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study

J Blanco, A Muriel-Bombín, V Sagredo, F Taboada… - Critical care, 2008 - Springer
Introduction Sepsis is a leading cause of admission to non-cardiological intensive care units
(ICUs) and the second leading cause of death among ICU patients. We present the first …

Prevalence and incidence of severe sepsis in Dutch intensive care units

A van Gestel, J Bakker, CPWM Veraart, BA van Hout - Critical care, 2004 - Springer
Introduction Severe sepsis is a dreaded consequence of infection and necessitates
intensive care treatment. Severe sepsis has a profound impact on mortality and on hospital …

Adequate antibiotic therapy prior to ICU admission in patients with severe sepsis and septic shock reduces hospital mortality

J Garnacho-Montero, A Gutiérrez-Pizarraya… - Critical care, 2015 - Springer
Introduction In patients with severe sepsis and septic shock as cause of Intensive Care Unit
(ICU) admission, we analyze the impact on mortality of adequate antimicrobial therapy …

The influence of gender on the epidemiology of and outcome from severe sepsis

Y Sakr, C Elia, L Mascia, B Barberis, S Cardellino… - Critical care, 2013 - Springer
Introduction The impact of gender on outcome in critically ill patients is unclear.
Weinvestigated the influence of gender on the epidemiology of severe sepsis andassociated …

Assessment of disease-severity scoring systems for patients with sepsis in general internal medicine departments

NO Ghanem-Zoubi, M Vardi, A Laor, G Weber… - Critical Care, 2011 - Springer
Introduction Due to the increasing burden on hospital systems, most elderly patients with
non-surgical sepsis are admitted to general internal medicine departments. Disease-severity …

Mortality and quality of life in the five years after severe sepsis

BH Cuthbertson, A Elders, S Hall, J Taylor… - Critical Care, 2013 - Springer
Introduction Severe sepsis is associated with high levels of morbidity and mortality, placing a
high burden on healthcare resources. We aimed to study outcomes in the five years after …

Characteristics, management, and in-hospital mortality among patients with severe sepsis in intensive care units in Japan: the FORECAST study

T Abe, H Ogura, A Shiraishi, S Kushimoto, D Saitoh… - Critical Care, 2018 - Springer
Background Sepsis is a leading cause of death and long-term disability in developed
countries. A comprehensive report on the incidence, clinical characteristics, and evolving …

Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]

GT Kinasewitz, SB Yan, B Basson, P Comp, JA Russell… - Critical care, 2004 - Springer
Abstract Introduction PROWESS (Recombinant Human Activated Protein C Worldwide
Evaluation in Severe Sepsis) was a phase III, randomized, double blind, placebo controlled …

Sepsis is a major determinant of outcome in critically ill HIV/AIDS patients

AM Japiassú, RT Amâncio, EC Mesquita, DM Medeiros… - Critical Care, 2010 - Springer
Introduction New challenges have arisen for the management of critically ill HIV/AIDS
patients. Severe sepsis has emerged as a common cause of intensive care unit (ICU) …

Epidemiology of sepsis in Norway in 1999

H Flaatten - Critical care, 2004 - Springer
Introduction Sepsis and severe sepsis are asociated with high hospital mortality. Little is
known about the occurrence of sepsis in general hospital populations. The goal of the …