Spinal serotonergic pathways provide inhibitory and excitatory modulation of sensory,
autonomic, and motor processing. After spinal cord injury (SCI), the acute inflammatory …

The early inflammatory response to spinal cord injury (SCI) causes significant secondary
damage. Strategies that nonselectively suppress inflammation have not improved outcomes …

This study was initiated due to an NIH “Facilities of Research-Spinal Cord Injury” contract to
support independent replication of published studies. Transient blockage of the …

Acute administration of a monoclonal antibody (mAb) raised against the CD11d subunit of
the leukocyte CD11d/CD18 integrin after spinal cord injury (SCI) in the rat greatly improves …

Object After spinal cord injury (SCI) leukocytes infiltrate the injured cord, causing significant
damage and further impairment of functional recovery. The leukocyte integrin α4β1 is crucial …

Abstract Changes in descending serotonergic innervation of spinal neural activity have been
implicated in symptoms of paralysis, spasticity, sensory disturbances and pain following …

Acute administration of a mononclonal antibody (mAb) raised against the CD11d subunit of
the leukocyte CD11d/CD18 integrin after spinal cord injury (SCI) in the rat greatly improves …

Traumatic injury to the spinal cord triggers a systemic inflammatory response syndrome
(SIRS), in which inflammatory cells from the circulation invade organs such as the liver, lung …

The accumulation of inflammatory cells in the lesion of a spinal cord injury (SCI) enhances
secondary damage, resulting in further neurological impairment. High-dose …

Spinal cord injury (SCI) is a devastating event with a tremendous impact in the life of the
affected individual and family. Traumatic injuries related to motor vehicle accidents, falls …