Angiotensin (Ang) II is not only generated in the circulation by renin and angiotensin-
converting enzyme (ACE) but also is produced locally in numerous organs including kidney …

Since the first identification of renin by Tigerstedt and Bergmann in 1898, the renin-
angiotensin system (RAS) has been extensively studied. The current view of the system is …

While the circulating renin-angiotensin system (RAS) plays an important role in short-term
maintenance of cardiovascular homeostasis, recent studies point to a role in long-term …

The renin–angiotensin system (RAS) plays an important role in regulating arterial pressure,
blood volume, thirst, cardiac function, and cellular growth. Both a circulating and multiple …

Since the discovery of renin as a pressor substance in 1898, the renin-angiotensin (RAS)
system has been extensively studied because it remains a prime candidate as a causative …

In its classical view, the renin angiotensin system (RAS) was defined as an endocrine
system involved in blood pressure regulation and body electrolyte balance. However, the …

The renin–angiotensin system (RAS), critically involved in the control of blood pressure and
volume homeostasis, is a dual system comprising a circulating component and a local tissue …

More than a century after its discovery, the physiological implications of the renin–
angiotensin system (RAS) continue to expand, with the identification of new components …

The renin–angiotensin system (RAS) is now regarded as an integral component in not only
the development of hypertension, but also in physiologic and pathophysiologic mechanisms …

The renin-angiotensin system (RAS) is well-recognized as one of the oldest and most
important regulators of arterial blood pressure, cardiovascular, and renal function. New …