The discovery of cisplatin in 1965 and its subsequent approval as an anticancer drug in
1978, paved the way for advances in anticancer platinum-based drugs.[1] However, cisplatin …

The N-heterocyclic carbene (NHC) precursor 2-pyridin-2-yl-2H-imidazo [1, 5-a] pyridin-4-
ylium hexafluorophosphate (1· HPF6) was used to synthesize various Ag and Au complexes …

Abstract Cyclic (Alkyl)(Amino) Carbenes (CAACs) have become forceful ligands for gold due
to their ability to form very strong ligand‐metal bonds. Inspired by the success of Auranofin …

Starting from the proligand 1-methyl-2-pyridin-2-yl-2H-imidazo [1, 5-a] pyridin-4-ylium
chloride (1 HCl), three novel complexes [Ag (1) Cl](2),[Au (1) Cl](3) and [Au (1) Cl3](4) were …

Two novel gold carbene compounds, namely, chlorido (1-butyl-3-methyl-imidazole-2-
ylidene) gold (I)(1) and bis (1-butyl-3-methyl-imidazole-2-ylidene) gold (I)(2), were prepared …

New gold (I) complexes containing two 1-[2-(diethylamino) ethyl] imidazolydene ligands
have been synthesized and characterized. The X-ray structures of two key compounds are …

A series of organometallic AuI N‐heterocyclic carbene (NHC) complexes was synthesized
and characterized for anticancer activity in four human cancer cell lines. The compounds' …

A series of Au (I) and Au (III) mono-, homobis-, and heterobis (carbene) complexes,[AuCl
(FPyr)](2),[Au (i Pr2-bimy) 2] PF6 (3),[Au (FPyr) 2] PF6 (4),[Au (FPyr)(i Pr2-bimy)] PF6 …

Three structurally related gold (I) carbene complexes with bulky hydrophobic ligands ie 1–3
were investigated in solution for further consideration as candidate anticancer agents …

Gold (I) N-heterocyclic carbenes (Au (I)-NHCs) are among the most widely investigated
class of complexes exhibiting cytotoxic potential towards a wide range of cancers. We …