Aim: Platelet function is intricately linked to the pathophysiology of critical Illness, and some
studies have shown that antiplatelet therapy (APT) may decrease mortality and incidence of …

Background Antiplatelet agents are commonly used for cardiovascular diseases, but their
pleiotropic effects in critically ill patients are controversial. We therefore performed a meta …

Antiplatelet therapy is an attractive treatment option for critically ill patients. However, more
evidence on the benefit of this therapy is required. We searched the PubMed and Embase …

Background Antiplatelet therapy may attenuate the undesirable effects of platelets on the
inflammatory cascades in critical illness. The objective of this study was to evaluate the …

Background Acute lung injury (ALI) is a potentially fatal lung disease with few treatment
options. Platelet activation is a key component of ALI pathophysiology and may provide an …

Background Acute respiratory distress syndrome (ARDS) is a life-threatening condition with
high mortality that imposes a serious medical burden. Antiplatelet therapy is a potential …

Acute respiratory distress syndrome (ARDS) is a common and devastating syndrome that
contributes to serious morbidities and mortality in critically ill patients. No known …

Purpose Abnormal platelet activation plays an important role in the development of sepsis.
The effect of antiplatelet drugs on the outcome of patients with sepsis remains unclear. This …

Objective: Platelet activation has been implicated in microvascular thrombosis and organ
failure. We tested the hypothesis that antiplatelet drugs favorably affect outcome in patients …

Background. Sepsis is characterized by dysfunctional activation of platelets, and antiplatelet
therapy could improve the outcomes of septic patients. Methods. We performed a …