Association between pre-ICU aspirin administration and ARDS mortality in the MIMIC-IV database: A cohort study

Y Yu, D Yang, Q Wang, J Li - Pulmonary Pharmacology & Therapeutics, 2024 - Elsevier
Abstract Background Acute Respiratory Distress Syndrome (ARDS) is a severe condition
with high mortality and morbidity rates. Evidence on the effectiveness of pharmacological …

Antiplatelet therapy and outcome in COVID-19: the health outcome predictive evaluation registry

F Santoro, IJ Nuñez-Gil, E Vitale, MC Viana-Llamas… - Heart, 2022 - heart.bmj.com
Background Standard therapy for COVID-19 is continuously evolving. Autopsy studies
showed high prevalence of platelet-fibrin-rich microthrombi in several organs. The aim of the …

Thrombocytopenia impairs host defense during murine Streptococcus pneumoniae pneumonia

FE van den Boogaard, M Schouten… - Critical care …, 2015 - journals.lww.com
Objectives: Streptococcus pneumoniae is the most common causative pathogen in
community-acquired pneumonia. In patients, thrombocytopenia is correlated with an …

Platelet Count During Course of Cardiogenic Shock

T Schupp, J Rusnak, J Forner, J Dudda, T Bertsch… - ASAIO …, 2024 - journals.lww.com
The study investigates the prognostic value of the platelet count in patients with cardiogenic
shock (CS). Limited data regarding the prognostic value of platelets in patients suffering from …

An increase in mean platelet volume after admission is associated with higher mortality in critically ill patients

FG Zampieri, OT Ranzani, V Sabatoski… - Annals of intensive …, 2014 - Springer
Background Platelet activation and consumption are common in critically ill patients and are
associated with poorer prognosis. Mean platelet volume is a simple surrogate for platelet …

Prevention of the adult respiratory distress syndrome with dipyridamole

JL VINCENT, S Brimioulle, J Berré… - Critical care …, 1985 - journals.lww.com
Because the formation of platelet thrombi has been incriminated in the development of the
adult respiratory distress syndrome (ARDS), we tested trie hypothesis that early …

Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced intensive care unit mortality: a prospective analysis

AJ Boyle, S Di Gangi, UI Hamid, LJ Mottram… - Critical Care, 2015 - Springer
Introduction Acute respiratory distress syndrome (ARDS) is a common clinical syndrome
with high mortality and long-term morbidity. To date there is no effective pharmacological …

Antiplatelet therapy: a double-edged sword in head injury?

C Beynon, OW Sakowitz - Critical Care, 2013 - Springer
Antiplatelet therapy for the treatment of cardiovascular diseases is common in the ageing
population. Whether this therapy exacerbates brain injury after head trauma is an important …

[HTML][HTML] Effect of antiplatelet therapy on survival and organ support–free days in critically ill patients with COVID-19: a randomized clinical trial

CA Bradbury, PR Lawler, SJ Stanworth, BJ McVerry… - Jama, 2022 - ncbi.nlm.nih.gov
Interventions Patients were randomized to receive either open-label aspirin (n= 565), a
P2Y12 inhibitor (n= 455), or no antiplatelet therapy (control; n= 529). Interventions were …

What really matters with thrombocytopenia: absolute value, timing, etiology or management?

F Reizine, C Aubron - Intensive Care Medicine, 2024 - Springer
We read with great interest the article of the PLOT-ICU study performed by Anthon et al.
deciphering thrombocytopenia and platelet transfusion landscapes in patients admitted in …