Background The effects of aspirin in preventing the occurrence of acute respiratory distress
syndrome (ARDS)/acute lung injury (ALI) among adult patients are controversial. We aimed …

Sepsis is defined as the systemic response to infection and is associated with a significant
mortality rate. The role of platelets in sepsis remains incompletely understood (Fig. 1). Under …

Objective Platelet (PLT) engages in immune and inflammatory responses, all of which are
related to the prognosis of critically ill patients. Although thrombocytopenia at ICU admission …

Objective: Acute respiratory distress syndrome is a common complication of critical illness,
with high mortality and limited treatment options. Preliminary studies suggest that potentially …

Kor et al. recently published the results of the LIPS-A trial (1). In this national multicenter
randomized controlled trial, early aspirin administration (325 mg loading dose then 81 …

Platelets play a major role in the thromboembolic diseases and upon vascular injury,
especially arterial vascular injury. These platelets rapidly adhere to the exposed …

Platelets play a central role in atherothrombosis and subsequent development of acute
coronary syndromes (ACS). The understanding of this process has driven a large body of …

Thrombocytopenia or receipt of antiplatelet drugs, with or without bleeding, is a common
indication for platelet transfusions in the ICU. However, there is almost no evidence base for …

Background The epidemiology of thrombocytopenia in critically ill patients has not been well
characterized. The objective of this study was to systematically review the prevalence …

Background. Refractoriness to platelet transfusion is an understudied phenomenon in
critically ill patients. Our objective was to evaluate the prevalence, risk factors, and clinical …