As part of a program to develop methods for dosimetry of exposure to sulfur mustard, we
developed immunochemical methods for the detection of the major adduct, N7-[2 …

As part of a program to develop methods for verification of alleged exposure to sulfur
mustard, we synthesized and characterized the adducts most likely formed by alkylation of …

Sulfur mustard is acutely toxic to the skin, eyes, and respiratory tract, and is considered
carcinogenic to humans by the IARC. Since all of these toxicities are thought to be initiated …

A standard operating procedure has been developed for an immunoslotblot assay of sulfur
mustard adducts to DNA in human blood and skin for use in a field laboratory. A minimum …

Since the toxicities of sulfur mustard are attributed to DNA alkylation, levels of DNA
modification in exposed cells should correlate with the intensity of exposure. We have found …

Sulphur mustard is a primary carcinogenic, cytotoxic and strongly vesicant agent which has
been used as a chemical warfare agent since World War I. We are engaged in the …

Sulphur mustard (SM) is known as an efficient vesicating agent as well as a carcinogenic
chemical. This warfare agent remains a threat for both civilians and militaries. DNA …

Sulfur mustard (SM) is an old chemical warfare agent causing blisters (vesicant). Skin
toxicity is thought to be partly caused by SM induced DNA damage. SM and the hemi …

In order to provide a quantitative basis for pretreatment and therapy of intoxications with
sulfur mustard (SM) the toxicokinetics of this agent as well as its major DNA-adduct were …

Sulfur mustard (SM) is an old chemical warfare but it remains a threat to both militaries and
civilians. SM mainly targets skin, eyes and lungs and diffuses to internal organs. At the …