The use of small animal imaging in respiratory disease drug discovery
The expansion of scientific knowledge and technology over the past decades did not result
in an increased rate of drug discoveries for respiratory diseases. Despite the identification of …
in an increased rate of drug discoveries for respiratory diseases. Despite the identification of …
A view on imaging in drug research and development for respiratory diseases
CJA van Echteld, N Beckmann - Journal of Pharmacology and Experimental …, 2011 - ASPET
With the incidence of respiratory diseases increasing throughout the world, new therapies
are needed. This review provides a short overview of different imaging techniques of interest …
are needed. This review provides a short overview of different imaging techniques of interest …
[HTML][HTML] An official ATS conference proceedings: advances in small-animal imaging application to lung pathophysiology
EXECUTIVE SUMMARY The American Thoracic Society convened a workshop,“Advances
in Small Animal Imaging: Application to Lung Pathophysiology,” to identify cutting-edge …
in Small Animal Imaging: Application to Lung Pathophysiology,” to identify cutting-edge …
Noninvasive small rodent imaging: significance for the 3R principles
N Beckmann, B Ledermann - Small Animal Imaging: Basics and Practical …, 2017 - Springer
Minimizing potential pain and distress as well as the number of animals in biomedical
experimentation and in the drug discovery and development process is not only an ethical …
experimentation and in the drug discovery and development process is not only an ethical …
Noninvasive small rodent imaging: significance for the 3R principles
N Beckmann, P Maier - Small Animal Imaging: Basics and Practical Guide, 2011 - Springer
Minimizing potential pain and distress as well as the number of animals in biomedical
experimentation and in the drug discovery and development process is not only a moral …
experimentation and in the drug discovery and development process is not only a moral …
Innovative Diagnostics Enhances and Advances the Impact of In Vivo Small‐Animal Imaging in Drug Discovery and Pharmaceutical Development
A Briel - Modern Biopharmaceuticals: Recent Success Stories, 2013 - Wiley Online Library
The ambitious strategic plan of the National Institutes of Health–known as the NIH Roadmap
for Medical Research 2002 and 2006–stresses the greater need to identify biological …
for Medical Research 2002 and 2006–stresses the greater need to identify biological …
Applications of small-animal molecular imaging in drug development
The gauntlet for a new drug to succeed is a daunting one. The reduction in the time and cost
required for modern drug discovery and development serves as a crucial need. An important …
required for modern drug discovery and development serves as a crucial need. An important …
Noninvasive imaging of experimental lung fibrosis
Small animal models of lung fibrosis are essential for unraveling the molecular mechanisms
underlying human fibrotic lung diseases; additionally, they are useful for preclinical testing of …
underlying human fibrotic lung diseases; additionally, they are useful for preclinical testing of …
Imaging in drug discovery and early clinical trials
M Rudin, EE Kim - 2007 - Soc Nuclear Med
In recent years, drug discovery has evolved into a distinct branch of science. The impact of
genomics on biomedical research and the development of efficient technology platforms …
genomics on biomedical research and the development of efficient technology platforms …
Preclinical Imaging for Laboratory Rodents
P Chaudhari - Essentials of Laboratory Animal Science: Principles …, 2021 - Springer
Laboratory animals play an important role in biomedical research and act as a backbone of
new drug research and development. Biomedical research is primarily dependent on …
new drug research and development. Biomedical research is primarily dependent on …