Role of extracellular vesicles in liver diseases and their therapeutic potential

E Kostallari, S Valainathan, L Biquard, VH Shah… - Advanced drug delivery …, 2021 - Elsevier
More than eight hundred million people worldwide have chronic liver disease, with two
million deaths per year. Recurring liver injury results in fibrogenesis, progressing towards …

Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets

G Szabo, F Momen-Heravi - Nature reviews Gastroenterology & …, 2017 - nature.com
Extracellular vesicles (EVs) are membranous vesicles originating from different cells in the
liver. The pathophysiological role of EVs is increasingly recognized in liver diseases …

[HTML][HTML] Extracellular vesicles in non-alcoholic and alcoholic fatty liver diseases

A Eguchi, AE Feldstein - Liver research, 2018 - Elsevier
Fatty liver diseases, non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease
(ALD) are the most common causes of chronic liver diseases around the world. NAFLD and …

[HTML][HTML] Extracellular vesicles in liver disease and beyond

L Morán, FJ Cubero - World journal of gastroenterology, 2018 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are membrane-derived vesicles which can be released by
different cell types, including hepatocytes, hepatic stellate cells and immune cells in normal …

[HTML][HTML] Extracellular vesicles in hepatology: Physiological role, involvement in pathogenesis, and therapeutic opportunities

M Azparren-Angulo, F Royo, E Gonzalez… - Pharmacology & …, 2021 - Elsevier
Since the first descriptions of hepatocyte-released exosome-like vesicles in 2008, the
number of publications describing Extracellular Vesicles (EVs) released by liver cells in the …

Emerging role of extracellular vesicles in liver diseases

H Malhi - … Journal of Physiology-Gastrointestinal and Liver …, 2019 - journals.physiology.org
Extracellular vesicles (EVs) are membrane-defined nanoparticles released by most cell
types. The EVs released by cells may differ quantitatively and qualitatively from …

Extracellular vesicle therapeutics for liver disease

DA Borrelli, K Yankson, N Shukla, G Vilanilam… - Journal of Controlled …, 2018 - Elsevier
Extracellular vesicles (EVs) are endogenous nanoparticles that play important roles in
intercellular communication. Unmodified and engineered EVs can be utilized for therapeutic …

Extracellular vesicles: a therapeutic option for liver fibrosis

S Bruno, G Chiabotto, G Camussi - International Journal of Molecular …, 2020 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous population of small membrane vesicles
released by all types of cells in both physiological and pathological conditions. EVs shuttle …

Extracellular vesicles in non-alcoholic fatty liver disease and alcoholic liver disease

D Wu, H Zhu, H Wang - Frontiers in Physiology, 2021 - frontiersin.org
As the largest vital solid organ in the body, liver is consisting of multiple types of cells
including hepatocytes, Kupffer cell, hepatic stellate cells (HSCs), liver sinusoidal endothelial …

Extracellular vesicles as biomarkers in liver disease

R Muñoz-Hernández, Á Rojas, S Gato… - International Journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) are membrane-derived vesicles released by a variety of cell
types, including hepatocytes, hepatic stellate cells, and immune cells in normal and …