The role of epigenetic inactivation of secreted frizzled‑related protein 2 (SFRP2) and its
functions in the development of oral squamous cell carcinoma (OSCC) remain to be …

Secreted frizzled-related proteins (SFRPs), the first identified Wnt antagonists, have been
well recognized as tumor suppressors in multiple human cancers through suppressing the …

AIM: To investigate the expression and methylation status of the secreted frizzled-related
protein 2 (SFRP2) in esophageal squamous cell carcinoma (ESCC) and explore its role in …

Background Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRPs family
that modulates the Wnt signal transduction pathway. Recent studies have showed down …

Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted
glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to …

Background/Aims: Choriocarcinoma (CC) is a highly aggressive gestational trophoblastic
neoplasia; however, the underlying molecular mechanisms of its invasiveness and …

Objective: Our aim of the study was to investigate the expression level and methylation
status of the secreted frizzled-related protein 2 in esophageal squamous cell carcinoma and …

It has been documented that secreted frizzled-related protein 1 (SFRP1) is epigenetically
silenced in laryngeal carcinoma. However, the function of SFRP1 in laryngeal carcinoma …

Secreted frizzled-related protein (SFRP) 2, an identified member of the SFRPs family of
molecules, is often methylated in human cancers and its down-regulation is closely related …

Abstract Secreted frizzled‐related protein‐5 (sFRP‐5) has been identified as 1 of the
secreted antagonists that bind Wnt protein. However, the functional significance of sFRP‐5 …