Replication of human immunodeficiency virus type 1 (HIV-1) was inhibited by stable
intracellular expression of antisense RNA in the human T-lymphoid cell line Jurkat. When …

Inhibition of human immunodeficiency virus type 1 (HIV-1) replication was demonstrated by
using tat-and rev-directed antisense oligoribonucleotides 68 and 69 nucleotides in length. In …

The antiviral activities of intracellularly expressed antisense RNAs complementary to the
human immunodeficiency virus type 1 (HIV-1) pol, vif, and env genes and the 3′ long …

Antisense RNA, transcribed intracellularly from constitutive expression cassettes, inhibits the
replication of the human immunodeficiency virus type 1 (HIV-1) as demonstrated by a …

The effect of the expression of antisense RNA against the human immunodeficiency virus
(HIV) genome in a human T-cell line CEM on HIV replication was investigated. A 2.7 …

Human immunodeficiency virus type 1 (HIV-1) primarily infects CD4+ lymphocytes and
macrophages and causes AIDS in humans. Retroviral vectors allowing neomycin …

Antisense RNA has proven a potent inhibitor of gene expression and has the potential to
inhibit retroviral replication at a number of stages in the virus life cycle by targeting both viral …

We have investigated two regions of the viral RNA of human immunodeficiency virus type 1
(HIV-1) as potential targets for antisense oligonucleotides. An oligodeoxynucleotide targeted …

Antisense RNA, which has a sequence complementary to mRNA, may provide the basis for
antiviral therapies of high selectivity. We have explored the inhibitory effect of six antisense …

Intracellular expression of antisense transcripts was evaluated for its potential to interfere
with human immunodeficiency virus type 1 (HIV-1) replication. Retroviral vectors encoding …