Limits to anatomical accuracy of diffusion tractography using modern approaches

KG Schilling, V Nath, C Hansen, P Parvathaneni… - Neuroimage, 2019 - Elsevier
Diffusion MRI fiber tractography is widely used to probe the structural connectivity of the
brain, with a range of applications in both clinical and basic neuroscience. Despite …

Challenges in diffusion MRI tractography–Lessons learned from international benchmark competitions

KG Schilling, A Daducci, K Maier-Hein… - Magnetic resonance …, 2019 - Elsevier
Diffusion MRI (dMRI) fiber tractography has become a pillar of the neuroimaging community
due to its ability to noninvasively map the structural connectivity of the brain. Despite …

Diffusion MRI fiber tractography of the brain

B Jeurissen, M Descoteaux, S Mori… - NMR in …, 2019 - Wiley Online Library
The ability of fiber tractography to delineate non‐invasively the white matter fiber pathways
of the brain raises possibilities for clinical applications and offers enormous potential for …

[HTML][HTML] TractoFlow: A robust, efficient and reproducible diffusion MRI pipeline leveraging Nextflow & Singularity

G Theaud, JC Houde, A Boré, F Rheault, F Morency… - Neuroimage, 2020 - Elsevier
Diffusion MRI tractography processing pipeline requires a large number of steps (typically
20+ steps). If parameters of these steps, number of threads, and random seed generators …

[HTML][HTML] Microstructure informed tractography: pitfalls and open challenges

A Daducci, A Dal Palú, M Descoteaux… - Frontiers in …, 2016 - frontiersin.org
One of the major limitations of diffusion MRI tractography is that the fiber tracts recovered by
existing algorithms are not truly quantitative. Local techniques for estimating more …

Quantitative evaluation of 10 tractography algorithms on a realistic diffusion MR phantom

P Fillard, M Descoteaux, A Goh, S Gouttard… - Neuroimage, 2011 - Elsevier
As it provides the only method for mapping white matter fibers in vivo, diffusion MRI
tractography is gaining importance in clinical and neuroscience research. However, despite …

When tractography meets tracer injections: a systematic study of trends and variation sources of diffusion-based connectivity

DB Aydogan, R Jacobs, S Dulawa… - Brain Structure and …, 2018 - Springer
Tractography is a powerful technique capable of non-invasively reconstructing the structural
connections in the brain using diffusion MRI images, but the validation of tractograms is …

[HTML][HTML] Using diffusion MRI data acquired with ultra-high gradient strength to improve tractography in routine-quality data

C Maffei, C Lee, M Planich, M Ramprasad, N Ravi… - Neuroimage, 2021 - Elsevier
The development of scanners with ultra-high gradient strength, spearheaded by the Human
Connectome Project, has led to dramatic improvements in the spatial, angular, and diffusion …

[HTML][HTML] Diffusion MRI and anatomic tracing in the same brain reveal common failure modes of tractography

G Grisot, SN Haber, A Yendiki - Neuroimage, 2021 - Elsevier
Anatomic tracing is recognized as a critical source of knowledge on brain circuitry that can
be used to assess the accuracy of diffusion MRI (dMRI) tractography. However, most prior …

Brain connections derived from diffusion MRI tractography can be highly anatomically accurate—if we know where white matter pathways start, where they end, and …

KG Schilling, L Petit, F Rheault, S Remedios… - Brain Structure and …, 2020 - Springer
MR Tractography, which is based on MRI measures of water diffusivity, is currently the only
method available for noninvasive reconstruction of fiber pathways in the brain. However, it …