Inhibitory effect of ginsenoside Rg1 on lipopolysaccharide-induced microglial activation in mice
JF Hu, XY Song, SF Chu, J Chen, HJ Ji, XY Chen… - Brain Research, 2011 - Elsevier
Microglial activation plays a pivotal role in the pathogenesis of neurodegenerative diseases
by producing various pro-inflammatory cytokines and nitric oxide (NO). In the paper, the anti …
by producing various pro-inflammatory cytokines and nitric oxide (NO). In the paper, the anti …
[HTML][HTML] Gastrodin inhibits expression of inducible NO synthase, cyclooxygenase-2 and proinflammatory cytokines in cultured LPS-stimulated microglia via MAPK …
JN Dai, Y Zong, LM Zhong, YM Li, W Zhang, LG Bian… - PloS one, 2011 - journals.plos.org
Background Microglial activation plays an important role in neurodegenerative diseases by
producing several proinflammatory enzymes and proinflammatory cytokines. The phenolic …
producing several proinflammatory enzymes and proinflammatory cytokines. The phenolic …
Guggulipid and nimesulide differentially regulated inflammatory genes mRNA expressions via inhibition of NF-kB and CHOP activation in LPS-stimulated rat …
Neuroinflammation is an integral part of neurodegenerative diseases. Lipo-polysacharide
(LPS) induces reactive astrogliosis, the cellular manifestation of neuroinflammation, in …
(LPS) induces reactive astrogliosis, the cellular manifestation of neuroinflammation, in …
Anti-inflammatory mechanism of ginseng saponins in activated microglia
JS Park, EM Park, DH Kim, K Jung, JS Jung… - Journal of …, 2009 - Elsevier
In the present study, we investigated the effect of ginseng extract (KRG) and total saponins
(GTS) on microglial activation. KRG and GTS inhibited LPS-induced expression of iNOS …
(GTS) on microglial activation. KRG and GTS inhibited LPS-induced expression of iNOS …
[HTML][HTML] Polysaccharides from Ganoderma lucidum attenuate microglia-mediated neuroinflammation and modulate microglial phagocytosis and behavioural …
Q Cai, Y Li, G Pei - Journal of neuroinflammation, 2017 - Springer
Background Ganoderma lucidum (GL) has been widely used in Asian countries for
hundreds of years to promote health and longevity. The pharmacological functions of which …
hundreds of years to promote health and longevity. The pharmacological functions of which …
Development and characterisation of mgTHP-1, a novel in vitro model for neural macrophages with microglial characteristics
E Kodosaki, A Daniels-Morgan, N Hassan… - Neurological …, 2024 - Taylor & Francis
Neuroinflammation is primarily characterised by activation of the brain's resident
macrophages–the microglia. However, other central nervous system (CNS) cells also …
macrophages–the microglia. However, other central nervous system (CNS) cells also …
High-mobility group box 1, an endogenous ligand of toll-like receptors 2 and 4, induces astroglial inflammation via nuclear factor kappa B pathway
EA Al-Ofi, BS Al-Ghamdi - Folia morphologica, 2019 - journals.viamedica.pl
Background: Neuroinflammation has a definitive role in neurodegenerative diseases, such
as Parkinson's and Alzheimer's disease. In addition to its pathoge-nic ligands, toll-like …
as Parkinson's and Alzheimer's disease. In addition to its pathoge-nic ligands, toll-like …
[HTML][HTML] The TSPO ligands 2-Cl-MGV-1, MGV-1, and PK11195 differentially suppress the inflammatory response of BV-2 microglial cell to LPS
M Azrad, N Zeineh, A Weizman, L Veenman… - International Journal of …, 2019 - mdpi.com
The 18 kDa Translocator Protein (TSPO) is a marker for microglial activation as its
expression is enhanced in activated microglia during neuroinflammation. TSPO ligands can …
expression is enhanced in activated microglia during neuroinflammation. TSPO ligands can …
Chitosan oligosaccharides suppress production of nitric oxide in lipopolysaccharide-induced N9 murine microglial cells in vitro
P Wei, P Ma, QS Xu, QH Bai, JG Gu, H Xi, YG Du… - Glycoconjugate …, 2012 - Springer
Chitosan oligosaccharides (COS) have been reported to exert many biological activities,
such as antioxidant, antitumor and anti-inflammatory effects. In the present study, we …
such as antioxidant, antitumor and anti-inflammatory effects. In the present study, we …
[HTML][HTML] Interleukin-10 protection against lipopolysaccharide-induced neuro-inflammation and neurotoxicity in ventral mesencephalic cultures
Y Zhu, X Chen, Z Liu, YP Peng, YH Qiu - International journal of molecular …, 2015 - mdpi.com
Interleukin (IL)-10, an anti-inflammatory cytokine, is expressed in the brain and can inhibit
microglial activation. Herein, we utilized lipopolysaccharide (LPS)-induced inflammatory …
microglial activation. Herein, we utilized lipopolysaccharide (LPS)-induced inflammatory …