Pregabalin is increasingly prescribed for neuropathic pain, generalised anxiety disorder and epilepsy but many patients discontinue treatment

B Wettermark, L Brandt, H Kieler… - International journal of …, 2014 - Wiley Online Library
Aim To assess prescribing patterns, sociodemographic characteristics and previous disease
history in patients receiving pregabalin. Methods An observational study using register data …

Oral gabapentinoids and nerve blocks for the treatment of chronic ocular pain

LR Small, A Galor, ER Felix, DB Horn, RC Levitt… - Eye & contact …, 2020 - journals.lww.com
Purpose: There is a recognition that nerve dysfunction can contribute to chronic ocular pain
in some individuals. However, limited data are available on how to treat individuals with a …

Patterns of pregabalin initiation and discontinuation after its subsidy in Australia

T Chiu, J Brett, SA Pearson… - British Journal of Clinical …, 2020 - Wiley Online Library
Following the 2013 public subsidy of pregabalin in Australia for neuropathic pain not
responding to other medicines, use and misuse increased substantially. We used …

Gabapentin in headache disorders: what is the evidence?

MD Perloff, RK Berlin, M Gillette, MJ Petersile… - Pain …, 2016 - academic.oup.com
Abstract Objective. Gabapentin (GBP), originally an antiepileptic drug, is more commonly
used in the treatment of pain, including headache disorders. Off-label GBP is used in …

Efficacy and tolerability of pregabalin as preventive treatment for migraine: a 3-month follow-up study

R Pizzolato, V Villani, L Prosperini, A Ciuffoli… - The Journal of …, 2011 - Springer
Migraine is a common neurological disorder and epidemiological studies have documented
its high social and economic impact. Unfortunately, preventive treatment is often insufficient …

Pregabalin: in the treatment of generalised anxiety disorder

JE Frampton, RH Foster - CNS drugs, 2006 - Springer
Abstract▲ Pregabalin, the pharmacologically active S-enantiomer of 3-aminomethyl-5-
methyl-hexanoic acid, is a structural analogue of GABA, although it is not active at GABA …

Peripheral edema with pregabalin

R Gallagher, N Apostle - CMAJ, 2013 - Can Med Assoc
A76-year-old woman with a 20-year his-tory of chronic pain in her back and legs caused by
degenerative spondylo listhesis, spinal stenosis, morbid obesity, ven ous insufficiency and …

Abuse and misuse of pregabalin and gabapentin: a systematic review update

KE Evoy, S Sadrameli, J Contreras, JR Covvey… - Drugs, 2021 - Springer
Background A 2017 systematic review (SR) identified 59 studies examining gabapentinoid
(pregabalin and gabapentin) misuse/abuse. Evidence of gabapentinoid misuse/abuse has …

Growing role of gabapentin in opioid-related overdoses highlights misuse potential and off-label prescribing practices

BM Kuehn - JAMA, 2022 - jamanetwork.com
Growing evidence of misuse and overdoses involving gabapentin—
ofteninconjunctionwithopioids—is drawing attention to substantial off-label prescribing of the …

Evaluation of pregabalin‐induced adverse events related to falls using the FDA adverse event reporting system and Japanese Adverse Drug Event Report databases

R Mukai, S Hasegawa, R Umetsu… - Journal of clinical …, 2019 - Wiley Online Library
What is known and objective Pregabalin is used for neuropathic and postherpetic pain and
generalized anxiety. The aim of this study was to obtain the onset profiles of adverse events …