Overexpression of long noncoding RNA H19 inhibits cardiomyocyte apoptosis in neonatal rats with hypoxic-ischemic brain damage through the miR-149-5p/LIF/PI3K …

L Zhang, T Liu, P Wang, Y Shen… - Biopreservation and …, 2021 - liebertpub.com
Hypoxic-ischemic brain damage (HIBD) is a leading cause of fatality and neural system
injury in neonates. This study aims to explore the effect of long noncoding RNA H19 on …

MicroRNA (miR)-429 promotes inflammatory injury by targeting kruppel-like factor 4 (KLF4) in neonatal pneumonia

L Zhang, HL Yan, H Wang, L Wang… - Current …, 2020 - ingentaconnect.com
Background: Neonatal pneumonia is a common disease in the neonatal period with a high
incidence and death. This study aimed to investigate the molecular mechanism and effect of …

microRNA-139-5p alleviates neurological deficit in hypoxic-ischemic brain damage via HDAC4 depletion and BCL-2 activation.

S Fei, L Cao, S Li - Brain Research Bulletin, 2021 - europepmc.org
Aim Studies paid much attention to the role of microRNAs (miRNAs) in hypoxic-ischemic
brain damage (HIBD) but not much to miR-139-5p. Thus, this study is to uncover the …

[HTML][HTML] MicroRNA-124 negatively regulates STAT3 to alleviate hypoxic-ischemic brain damage by inhibiting oxidative stress

J Geng, J Feng, F Ke, F Fang, X Jing, J Tang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Abstract MicroRNA-124 (miR-124) is implicated in various neurological diseases; however,
its significance in hypoxic-ischaemic brain damage (HIBD) remains unclear. This study …

RETRACTED: MicroRNA-132 protects hippocampal neurons against oxygen-glucose deprivation–induced apoptosis

ZZ Sun, ZY Lv, WJ Tian, Y Yang - International journal of …, 2017 - journals.sagepub.com
Hypoxic-ischemic brain injury (HIBI) results in death or long-term neurologic impairment in
both adults and children. In this study, we investigated the effects of microRNA-132 (miR …

LINC00938 alleviates hypoxia ischemia encephalopathy induced neonatal brain injury by regulating oxidative stress and inhibiting JNK/p38 MAPK signaling pathway

J Zhao, M Le, J Li, Q Huang, H Chen, W Zhang… - Experimental …, 2023 - Elsevier
Hypoxic-ischemic encephalopathy (HIE) is an important factor leading to permanent
damage of central nervous system (CNS) and even neonatal death. Long non-coding RNAs …

MicroRNA-210 suppresses junction proteins and disrupts blood-brain barrier integrity in neonatal rat hypoxic-ischemic brain injury

Q Ma, C Dasgupta, Y Li, L Huang, L Zhang - International journal of …, 2017 - mdpi.com
Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of
the serious complications associated with brain injury in neonatal hypoxic-ischemic …

MiRNA-210 induces microglial activation and regulates microglia-mediated neuroinflammation in neonatal hypoxic-ischemic encephalopathy

B Li, C Dasgupta, L Huang, X Meng… - Cellular & Molecular …, 2020 - nature.com
Neuroinflammation is a major contributor to secondary neuronal injury that accounts for a
significant proportion of final brain cell loss in neonatal hypoxic-ischemic encephalopathy …

Effects of microRNA-25 on cerebral ischemia/reperfusion injury-induced cell apoptosis

ZJZ Zhao-hua, HAOJF Zhi-chao… - Acta Anatomica …, 2018 - jpxb.bjmu.edu.cn
Objective To evaluate the role and the possible mechanisms of microRNA-25 (miR-25) in
regulating oxygen-glucose deprivation (OGD)/reperfusion (OGDR)-induced cell apoptosis in …

Protective effect of microRNA-138 against cerebral ischemia/reperfusion injury in rats

XJ Tang, MH Yang, G Cao, JT Lu… - Experimental and …, 2016 - spandidos-publications.com
MicroRNAs (miRs) serve a regulatory function in oxidative radical-mediated inflammation
and apoptosis during ischemia/reperfusion (IR) injury. Lipocalin 2 (Lcn-2), a target protein of …