Following immunization, lymph nodes dynamically expand and contract. The mechanical
and cellular changes enabling the early-stage expansion of lymph nodes have been …

Lymph nodes (LNs) dynamically expand in response to immunization, but the relationship
between LN expansion and the accompanying adaptive immune response is unclear. Here …

Mechanics drive lymph node expansion | Nature Immunology Skip to main content Thank you
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Emergent physical properties of tissues are not readily understood by reductionist studies of
their constituent cells. Here, we show molecular signals controlling cellular, physical, and …

Nanoparticles, microparticles, and other biomaterials are advantageous in vaccination
because these materials provide opportunities to modulate specific characteristics of …

Lymph nodes (LNs) comprise two main structural elements: fibroblastic reticular cells that
form dedicated niches for immune cell interaction and capsular fibroblasts that build a shell …

The secondary lymphoid organs (SLOs) undergo structural changes with age, which
correlates with diminishing immune responses against infectious disease. A growing body of …

Lymphatic endothelial cells (LECs) form the structure of the lymphatic vessels and the
sinuses of the lymph nodes, positioning them to be key players in many different aspects of …

Lymph nodes (LNs) are constructed of intricate networks of endothelial and mesenchymal
stromal cells. How these lymphoid stromal cells (LSCs) regulate lymphoid tissue remodeling …

Lymph node (LN) expansion during an immune response relies on the transient remodeling
of its vasculature. Although the mechanisms driving LN endothelial cell division are …