Cerebellar granule neurons (CGNs) are one of the most populous cells in the mammalian
brain. They express an outwardly rectifying potassium current, termed a “standing-outward” …

The potassium channels in the two-pore domain family are widely expressed and regulate
the excitability of neurons and other excitable cells. These channels have been shown to …

Cerebellar granule neurons express a standing outward (background) K+ current (IK, SO)
that regulates the resting membrane potential and cell excitability. As several tandem‐pore …

The two-pore-domain K+ channel, TASK-1, was recently shown to be a target of receptor-
mediated regulation in neurons and in adrenal glomerulosa cells. Here, we demonstrate that …

Two-pore domain potassium (K2P) channel expression is believed to underlie the
developmental emergence of a potassium leak conductance [IK (SO)] in cerebellar granule …

Tandem pore domain K+ channels (2P K+ channels) are responsible for background K+
currents. 2P K+ channels are the most numerous encoded K+ channels in the …

The TASK subfamily of two pore domain potassium channels (K2P) gives rise to leak
potassium currents, which contribute to the resting membrane potential of many neurons …

Recently, a new family of potassium channels with two pore domains in tandem and four
transmembrane segments has been identified. Seven functional mammalian channels have …

TASK‐1 and TASK‐3 are functional members of the tandem‐pore K+ (K2P) channel family,
and mRNAs for both channels are expressed together in many brain regions. Although …

We have isolated, by degenerate PCR, a complementary DNA encoding a novel two pore
domain potassium channel. This is the 7th functional member of the human tandem pore …