SUBSTANTIAL AGE-ADJUSTED REDUCTIONS IN CARDIO-vascular mortality and
morbidity over the past few decades are being challenged by increases in physical inactivity …

fromNHLBI gene-based treatments, and far more personalized approaches to CV prevention
and therapeutics. Large-scale clinical trials funded by the NHLBI during the past several …

Cardiovascular medicine currently lacks high-quality evidence needed to inform many
important decisions that patients, physicians, and other health care practitioners and health …

Previous decades have seen significant progress in the biological understanding of
cardiovascular disease, as well as major advances in computational and information …

Background—A clear need exists for a more systematic understanding of the epidemiology,
diagnosis, and management of cardiovascular diseases. More robust data are also needed …

Recent developments have highlighted the challenges facing cardiovascular clinical
research in global contemporary practice, particularly in North America, including shifting …

Health. As cardiovascular disease was emerging as the biggest threat to the nation's health,
and as threats of war loomed from Europe, Roosevelt declared,“Total defense... which the …

They accounted for 32% of the total deaths globally and contributed to 11% of the global
burden of disability adjusted life years (DALYs) in the year 2005 (1). The fast-changing …

Groups such as Healthy People 2010 [1] and the American Heart Association [101] have set
bold goals for reducing the risk of heart disease, stroke and other cardiovascular conditions; …

Conquering Atherosclerotic Cardiovascular Disease Substantial reductions in
cardiovascular mortality in the United States reflect the power of a system that catalyzes the …