Synthesis, Biological Activity, and Toxicity to Zebrafish Embryo of Benzamides Substituted with 1, 2, 4-Oxadiazole-Linked Pyrazole

Y Wang, C Wu, Z Li, J Wu, Y Chen, M Li… - … Agricultural Science & …, 2023 - ACS Publications
To explore novel pesticidal lead compounds with potential activity, a series of new
benzamide compounds substituted with 1, 2, 4-oxadiazole-linked pyrazole were designed …

[HTML][HTML] Synthesis, biological activity and toxicity to zebrafish of benzamides substituted with pyrazole-linked 1, 2, 4-oxadiazole

Y Shao, M Tu, S Yang, Y Wang, B Sun, J Shi, C Tan… - RSC …, 2022 - pubs.rsc.org
To find pesticidal lead compounds with high activity, a series of novel benzamides
substituted with pyrazole-linked 1, 2, 4-oxadiazole was designed and synthesized by using …

[HTML][HTML] Benzamides substituted with quinoline-linked 1, 2, 4-oxadiazole: Synthesis, biological activity and toxicity to zebrafish embryo

BL Sun, YY Wang, S Yang, MT Tu, YY Shao, Y Hua… - Molecules, 2022 - mdpi.com
To develop new compounds with high activity, broad spectrum and low-toxicity, 17
benzamides substituted with quinoline-linked 1, 2, 4-oxadiazole were designed using the …

[HTML][HTML] Structure-based Bioisosterism design, synthesis, biological activity and toxicity of 1, 2, 4-oxadiazole substituted benzamides analogues containing pyrazole …

MT Tu, YY Shao, S Yang, BL Sun, YY Wang, CX Tan… - Molecules, 2022 - mdpi.com
In order to discover pesticidal lead compounds with high activity and low toxicity, a series of
novel benzamides substituted with pyrazole-linked 1, 2, 4-oxadiazole were designed via …

[HTML][HTML] Synthesis and biological activity of benzamides substituted with pyridine-linked 1, 2, 4-oxadiazole

S Yang, XY Tian, TY Ma, L Dai, CL Ren, JC Mei, XH Liu… - Molecules, 2020 - mdpi.com
To find pesticidal lead compounds with high activity, a series of novel benzamides
substituted with pyridine-linked 1, 2, 4-oxadiazole were designed by bioisosterism, and …

[HTML][HTML] Novel Pyridyl–Oxazole Carboxamides: Toxicity Assay Determination in Fungi and Zebrafish Embryos

S Chen, DL Zhang, CL Ren, WQ Zou, XY Tian, XH Du… - Molecules, 2021 - mdpi.com
Eight novel pyridyl–oxazole carboxamides were evaluated against fungi and displayed
good fungicidal activities against Botrytis cinereal and Rhizoctonia solani. Preliminary …

[HTML][HTML] 1, 2, 4-Oxadiazole-based bio-isosteres of benzamides: Synthesis, biological activity and toxicity to zebrafish embryo

S Yang, CL Ren, TY Ma, WQ Zou, L Dai… - International Journal of …, 2021 - mdpi.com
To discover new compounds with broad spectrum and high activity, we designed a series of
novel benzamides containing 1, 2, 4-oxadiazole moiety by bioisosterism, and 28 …

Discovery of a new insecticide lead by optimizing a target-diverse scaffold: tetrazolinone derivatives

YP Luo, GF Yang - Bioorganic & medicinal chemistry, 2007 - Elsevier
In order to discover lead compounds with novel action mechanism, a series of tetrazolinone
derivatives bearing structurally diverse substituents, 1-aryl-4-substituted-1, 4-di-hydro-5H …

Synthesis and Biological Activities of Novel Pyrazole Amide Compounds Containing Substituted Oxazole Unit

LK Dai Hong, Q Zhou, Y Ni, C Qian, H Qian… - Chinese Journal of …, 2020 - sioc-journal.cn
In search of new pyrazole amide derivatives with wonderful bioactivities, fifteen novel
pyrazole amide compounds were designed and synthesized by introducing substituted …

Design, Synthesis, and Biological Activities of Novel Phenylpyrazole Derivatives Containing a Trifluoromethylselenyl Moiety

L Dong, W Chang, W Yang, Z Xu, J Cheng… - Journal of Agricultural …, 2023 - ACS Publications
Phenylpyrazole insecticides are widely used for crop protection and public sanitation by
blocking gamma-aminobutyric acid (GABA)-gated chloride channels and glutamate-gated …