Comparison of serology and molecular detection of common red cell antigens in multitransfused thalassemia major and sickle cell disease patients

A Shah, P Patel, K Patel, B Patel, K Jariwala… - … and Apheresis Science, 2020 - Elsevier
Background Serological testing for extended RHCcEe, Kell, Kidd and Duffy blood grouping
from multitransfused patients may not give correct blood grouping of the recipient. Hence …

[HTML][HTML] Challenges of blood transfusions in β-thalassemia

FT Shah, F Sayani, S Trompeter, E Drasar, A Piga - Blood reviews, 2019 - Elsevier
Patients with β-thalassemia major (BTM) require regular blood transfusions, supported by
appropriate iron chelation therapy (ICT), throughout their life. β-thalassemia is a global …

Prevalence and specificities of red cell alloantibodies among blood recipients in the Malaysian state of Kelantan

F Al-Joudi, AB Ali, MBH Ramli, S Ahmed… - Asian journal of …, 2011 - journals.lww.com
Background: Red blood cell (RBC) alloantibodies may be formed following exposure to RBC
antigens. In most cases, the alloimmunization develops during pregnancy or from previous …

Transfusion medicine in a developing country–Alloantibodies to red blood cells in multi-transfused patients in Saudi Arabia

AGMA Gader, AK Al Ghumlas… - Transfusion and Apheresis …, 2008 - Elsevier
BACKGROUND: Multiple transfusions are frequently complicated by alloimmunization. This
retrospective study aims to determine whether alloimmunization could be accounted for by …

Comparative study of alloimmunization against red cell antigens in sickle cell disease & thalassaemia major patients on regular red cell transfusion

K Jariwala, K Mishra, K Ghosh - Indian Journal of Medical …, 2019 - journals.lww.com
Methods: All sickle cell disease patients undergoing red cell transfusion between 2008 and
2016, were included. During this period, a large number of β-thalassaemia major patients …

Blood group genotyping in alloimmunized multi‐transfused thalassemia patients from Iran

R Sarihi, A Oodi, R Dadkhah Tehrani… - … Genetics & Genomic …, 2021 - Wiley Online Library
Objectives Serological methods may not be reliable for RBC antigen typing, especially in
multi‐transfused patients. The blood group systems provoking the most severe transfusion …

Predictors of red cell alloimmunization in Kurdish multi transfused patients with hemoglobinopathies in Iraq

MMN Al-Mousawi, NAS Al-Allawi, R Alnaqshabandi - Hemoglobin, 2015 - Taylor & Francis
Hemoglobinopathies are significant health problems in Iraq, including its Northern Kurdistan
region. One of the essential components of management of these disorders is regular …

Rh-matched transfusion through molecular typing for β-thalassemia patients is required and feasible in Chinese

CP Shao, CJ Zhao, CL Wu, H Xu, XD Wang… - Transfusion Medicine …, 2018 - karger.com
Background: Molecular typing for RHCE blood group alleles has been established in many
countries for patients and blood donors. In the Chinese literature nearly 80% of transfused …

Antibody screening and identification by gel method in thalassemic patients

A Azarkeivan, MH Ahmadi… - Scientific Journal of …, 2008 - bloodjournal.ir
Materials and Methods In a descriptive study 441 thalassemia patients having referred to
two thalassemic centers in Tehran and Ghazvin were studied. Data forms about blood …

Alloimmunization to red cells and the association of alloantibodies formation with splenectomy among transfusion-dependent β-thalassemia major/HbE patients

S Jansuwan, O Tangvarasittichai… - Indian journal of clinical …, 2015 - Springer
Severe hemolytic anemia in β-thalassemia major and β-thalassemias/HbE (β-TM) patients
requires giving blood transfusions. Chronic blood transfusions lead to iron overload …