Randomized comparison of platelet function monitoring to adjust antiplatelet therapy versus standard of care: rationale and design of the assessment with a double …

JP Collet, G Cayla, T Cuisset, S Elhadad, G Rangé… - American Heart …, 2011 - Elsevier
BACKGROUND: Individual response to oral antiplatelet therapy is subject to variability, and
bedside monitoring offers the opportunity of individualizing therapy for stent implantation …

Impact of aspirin and clopidogrel hyporesponsiveness in patients treated with drug-eluting stents: 2-year results of a prospective, multicenter registry study

TD Stuckey, AJ Kirtane, BR Brodie… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: In this analysis of 2-year outcomes in the ADAPT-DES (Assessment of Dual
AntiPlatelet Therapy with Drug-Eluting Stents) study, the authors sought to examine the …

Antiplatelet drug response variability and the role of platelet function testing: a practical guide for interventional cardiologists

DJ Angiolillo, S Suryadevara… - Catheterization and …, 2009 - Wiley Online Library
Antiplatelet therapy is the cornerstone of treatment for patients with acute coronary
syndrome and is also of particular importance in those who undergo percutaneous coronary …

[HTML][HTML] Bedside monitoring to adjust antiplatelet therapy for coronary stenting

JP Collet, T Cuisset, G Rangé, G Cayla… - … England Journal of …, 2012 - Mass Medical Soc
Background Patients' responses to oral antiplatelet therapy are subject to variation. Bedside
monitoring offers the opportunity to improve outcomes after coronary stenting by …

High on-treatment platelet reactivity as a risk factor for secondary prevention after coronary stent revascularization: a landmark analysis of the ARCTIC study

G Montalescot, G Range, J Silvain, JL Bonnet… - Circulation, 2014 - Am Heart Assoc
Background—Individualizing antiplatelet therapy after platelet function testing did not
improve outcome after coronary stenting in the Assessment by a Double Randomization of a …

Evaluation of individualized clopidogrel therapy after drug-eluting stent implantation in patients with high residual platelet reactivity: design and rationale of the …

MJ Price, PB Berger, DJ Angiolillo, PS Teirstein… - American heart …, 2009 - Elsevier
BACKGROUND: The inhibitory response to clopidogrel varies widely among individuals.
Data suggest that patients with high residual platelet reactivity despite clopidogrel therapy …

Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation

MJ Price, S Endemann, RR Gollapudi… - European heart …, 2008 - academic.oup.com
Aims The aim of this study was to determine whether platelet reactivity on clopidogrel
therapy, as measured by a point-of-care platelet function assay, is associated with …

Temporal variability in the antiplatelet effects of clopidogrel and aspirin after elective drug-eluting stent implantation

TG Nührenberg, C Stratz, S Leggewie… - Thrombosis and …, 2015 - thieme-connect.com
Given conflicting data on temporal variability in pharmacodynamic platelet responses to
clopidogrel, we investigated platelet reactivity on clopidogrel and aspirin for up to six months …

[HTML][HTML] Point-of-care platelet function assays demonstrate reduced responsiveness to clopidogrel, but not aspirin, in patients with Drug-Eluting Stent Thrombosis …

AR Hobson, G Petley, G Morton, KD Dawkins… - Thrombosis …, 2008 - Springer
Background To test the hypothesis that point-of-care assays of platelet reactivity would
demonstrate reduced response to antiplatelet therapy in patients who experienced Drug …

Platelet function monitoring to adjust antiplatelet therapy in elderly patients stented for an acute coronary syndrome (ANTARCTIC): an open-label, blinded-endpoint …

G Cayla, T Cuisset, J Silvain, F Leclercq… - The Lancet, 2016 - thelancet.com
Background Elderly patients are at high risk of ischaemic and bleeding events. Platelet
function monitoring offers the possibility to individualise antiplatelet therapy to improve the …