Circulating tumour cells in clinical practice: Methods of detection and possible characterization

M Alunni-Fabbroni, MT Sandri - Methods, 2010 - Elsevier
Circulating Tumour Cells (CTCs) can be released from the primary tumour into the
bloodstream and may colonize distant organs giving rise to metastasis. The presence of …

Circulating tumor cells (CTCs): detection methods and their clinical relevance in breast cancer

B Mostert, S Sleijfer, JA Foekens, JW Gratama - Cancer treatment reviews, 2009 - Elsevier
The enumeration of circulating tumor cells has long been regarded as an attractive
diagnostic tool, as circulating tumor cells are thought to reflect aggressiveness of the tumor …

[HTML][HTML] Circulating tumor cells in breast cancer

FC Bidard, C Proudhon, JY Pierga - Molecular oncology, 2016 - Elsevier
Over the past decade, technically reliable circulating tumor cell (CTC) detection methods
allowed the collection of large datasets of CTC counts in cancer patients. These data can be …

New technologies for the detection of circulating tumour cells

N Gerges, J Rak, N Jabado - British medical bulletin, 2010 - academic.oup.com
The vast majority of cancer-related death is due to the metastatic spread of the primary
tumour. Circulating tumour cells (CTC) are essential for establishing metastasis and their …

Challenges in circulating tumour cell research

C Alix-Panabières, K Pantel - Nature Reviews Cancer, 2014 - nature.com
During the past ten years, circulating tumour cells (CTCs) have received enormous attention
as new biomarkers and the subject of basic research. Although CTCs are already used in …

Molecular characterization of circulating tumor cells in breast cancer: challenges and promises for individualized cancer treatment

ES Lianidou, A Markou, A Strati - Cancer and Metastasis Reviews, 2012 - Springer
Abstract Blood testing using Circulating Tumor Cells (CTCs) has emerged as one of the
hottest fields in cancer diagnosis. Research on CTCs present nowadays a challenge, as …

Circulating tumor cells as promising novel biomarkers in solid cancers

ES Lianidou, A Strati, A Markou - Critical reviews in clinical …, 2014 - Taylor & Francis
The presence of circulating tumor cells (CTCs) in peripheral blood can serve as a “liquid
biopsy” approach and has thus emerged lately as one of the hottest fields in cancer …

Circulating tumor cells: advances in detection methods, biological issues, and clinical relevance

YF Sun, XR Yang, J Zhou, SJ Qiu, J Fan… - Journal of cancer research …, 2011 - Springer
Abstract Background Circulating tumor cells (CTCs) have long been considered a reflection
of tumor aggressiveness. Hematogenous spreading of CTCs from a primary tumor is a …

[HTML][HTML] Circulating tumor cells: finding the needle in the haystack

X Zhe, ML Cher, RD Bonfil - American journal of cancer research, 2011 - ncbi.nlm.nih.gov
Localized and metastatic cancers give rise to circulating tumor cells (CTCs) which are
detectable in the bloodstream. Recent studies have highlighted the prognostic significance …

The role of CTCs as tumor biomarkers

ES Lianidou, A Markou, A Strati - … : From biochemistry to clinic for a critical …, 2015 - Springer
Abstract Detection of Circulating Tumor Cells (CTCs) in peripheral blood can serve as a
“liquid biopsy” approach and as a source of valuable tumor markers. CTCs are rare, and …