Background: Nonnucleoside reverse transcription inhibitor (NNRTI)-based antiretroviral
therapy (ART) has been widely used as a first-line regimen for the treatment of HIV. This …

Objectives The aim of the study was to assess the prevalence, predictors and patterns of
genotypic resistance mutations in children after failure of World Health Organization …

Background Early recognition of antiretroviral therapy (ART) failure in resource limited
settings is a challenge given the limited laboratory facilities and trained personnel. This …

Background. The optimum strategy for stopping treatment with drugs that have different half-
lives in a combination regimen to minimize the risk of selecting drug-resistant viruses …

Objectives To evaluate the virological response and to describe the resistance profiles in the
case of failure after 6 months of first-line highly active antiretroviral therapy (HAART) in HIV-1 …

Background: Limited data exist on drug resistance and antiretroviral treatment (ART)
outcomes in HIV-1–infected children in West Africa. We determined the prevalence of …

Objective: To describe the prevalence of HIV-1 drug resistance mutations at the time of
treatment initiation in a large cohort of HIV-infected children previously exposed to single …

Objectives To assess long-term virological efficacy and the emergence of drug resistance in
children who receive antiretroviral treatment (ART) in rural Tanzania. Patients and methods …

BACKGROUND: Non-nucleoside reverse transcriptase inhibitor (NNRTI)-based highly
active antiretroviral therapy (HAART) has been the most affordable regimen for the HIV …

Importance Worldwide, the nonnucleoside reverse transcriptase inhibitors (NNRTIs)
efavirenz and nevirapine are commonly used in first-line antiretroviral regimens in both …