Incidence and management of complications of fibrinolytic, antiplatelet, and anticoagulant therapy

AG Rebeiz, CB Granger… - Fundamental and Clinical …, 2005 - api.taylorfrancis.com
The treatment of acute coronary syndromes (ACS) and percutaneous coronary intervention
(PCI) encompasses a wide spectrum of pharmacological strategies ranging from clot lysis in …

Antithrombotic agents: platelet inhibitors, anticoagulants, and fibrinolytics

KAA FOX, H White, JJS OPIE, BJ GERSH… - Drugs for the Heart E …, 2011 - books.google.com
The proaggregatory and antiaggregatory factors of the hemostatic system are normally finely
balanced, opposing mechanisms. To protect against vascular damage and the risk of …

Fibrinolytic, antithrombotic, and antiplatelet drugs in acute coronary syndromes

P Sinnaeve, F Van de Werf - The ESC Textbook of Intensive and …, 2015 - books.google.com
Antithrombotic therapy is a major cornerstone in the treatment for acute coronary syndromes,
as thrombus formation upon a plaque rupture or an erosion plays a pivotal role in non-ST …

The challenge of defining bleeding among patients with acute coronary syndromes

TW Wallace, SV Rao - Clinical cardiology, 2007 - Wiley Online Library
Advances in the management of patients with acute coronary syndromes (ACS), specifically,
the use of combined pharmacotherapy with antithrombotic and antiplatelet therapies and …

The relationship between bleeding and adverse outcomes in ACS and PCI: pharmacologic and nonpharmacologic modification of risk.

SV Manoukian - The Journal of invasive cardiology, 2010 - europepmc.org
Antithrombotic therapy, including antiplatelet and antithrombin agents, effectively reduces
the risk of ischemic events in patients with acute coronary syndromes (ACS) and those …

The balance between anti-ischemic efficacy and bleeding risk of antithrombotic therapy in percutaneous coronary intervention: a Yin-Yang paradigm.

JA Lardizabal, BK Joshi, JA Ambrose - The Journal of invasive …, 2010 - europepmc.org
Background The development of newer and more potent antithrombotic agents and
strategies has markedly reduced cardiovascular mortality and ischemic complications in …

Thrombosis in acute coronary syndromes and coronary interventions

TR Tolleson, RA Harrington - Platelet Glycoprotein IIb/IIIa Inhibitors in …, 1999 - Springer
Acute coronary syndromes (ACS), including unstable angina, non-ST elevation myocardial
infarction, and ST-elevation myocardial infarction, are the most commonly encountered …

Thrombin inhibitors in fibrinolysis: a Hobson's choice of alternatives

J Loscalzo - Circulation, 1996 - Am Heart Assoc
Legend holds that Tobias Hobson, the first Englishman to rent horses for hackney use,
offered potential customers one of two choices: take the horse nearest the door of his …

Predictors and impact of bleeding complications in percutaneous coronary intervention, acute coronary syndromes, and ST-segment elevation myocardial infarction

SV Manoukian - The American journal of cardiology, 2009 - Elsevier
Although the use of oral and intravenous antiplatelet and antithrombin therapy in the acute
and chronic settings of percutaneous coronary intervention (PCI), acute coronary syndromes …

Current antithrombotic agents for acute coronary syndromes: focus on bleeding risk

JP Bassand - International journal of cardiology, 2013 - Elsevier
The formation of an intravascular thrombus underlies the clinical symptoms associated with
acute coronary syndromes (ACS). Plaque rupture signals the recruitment and activation of …